Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View
Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideati...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Archives of Psychiatry Research
2021
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/26901/1/Sarcoidosis%20and%20Corticosteroid%20Therapy.pdf https://eprints.ums.edu.my/id/eprint/26901/2/Sarcoidosis%20and%20Corticosteroid%20Therapy1.pdf |
| _version_ | 1825714075112308736 |
|---|---|
| author | Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping |
| author_facet | Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping |
| author_sort | Mohd Amiruddin Mohd Kassim |
| collection | UMS |
| description | Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideations subsequently emerged, only to show partial response to antipsychotic treatment. Results: Sarcoidosis was treated with corticosteroids but serial thorax imaging shows minimal response. Corticosteroid was onboard throughout treatment, corresponding with non-remission of psychotic symptoms. There are persistent subjective cognitive difficulties but Mini Mental State Exam score is full. He is currently being treated with escitalopram, alprazolam and quetiapine. Conclusion: This case illustrated the dilemma between prolonging the corticosteroid therapy for sarcoidosis treatment and the psychiatric sequalae. While symptomatic antipsychotic treatment is effective, multi-disciplinary approach is imperative in determining the duration of the corticosteroid therapy. |
| first_indexed | 2024-03-06T03:06:24Z |
| format | Article |
| id | ums.eprints-26901 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:06:24Z |
| publishDate | 2021 |
| publisher | Archives of Psychiatry Research |
| record_format | dspace |
| spelling | ums.eprints-269012021-05-05T00:35:02Z https://eprints.ums.edu.my/id/eprint/26901/ Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping R Medicine (General) RA Public aspects of medicine Introduction and Methods: A man diagnosed with sarcoidosis developed partial retrograde amnesia followed by three months of depressive symptoms with panic attacks, which remitted with an antidepressant and a benzodiazepine. However, three months later hallucinations and overvalued persecutory ideations subsequently emerged, only to show partial response to antipsychotic treatment. Results: Sarcoidosis was treated with corticosteroids but serial thorax imaging shows minimal response. Corticosteroid was onboard throughout treatment, corresponding with non-remission of psychotic symptoms. There are persistent subjective cognitive difficulties but Mini Mental State Exam score is full. He is currently being treated with escitalopram, alprazolam and quetiapine. Conclusion: This case illustrated the dilemma between prolonging the corticosteroid therapy for sarcoidosis treatment and the psychiatric sequalae. While symptomatic antipsychotic treatment is effective, multi-disciplinary approach is imperative in determining the duration of the corticosteroid therapy. Archives of Psychiatry Research 2021 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/26901/1/Sarcoidosis%20and%20Corticosteroid%20Therapy.pdf text en https://eprints.ums.edu.my/id/eprint/26901/2/Sarcoidosis%20and%20Corticosteroid%20Therapy1.pdf Mohd Amiruddin Mohd Kassim and Ruziana Masiran and Pang, Nicholas Tze Ping (2021) Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View. Archives of Psychiatry Research, 57. pp. 93-98. ISSN 2671-2008 file:///C:/Users/user/Downloads/archives_vol_57_no_1_9%20(1).pdf |
| spellingShingle | R Medicine (General) RA Public aspects of medicine Mohd Amiruddin Mohd Kassim Ruziana Masiran Pang, Nicholas Tze Ping Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title | Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title_full | Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title_fullStr | Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title_full_unstemmed | Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title_short | Sarcoidosis and Corticosteroid Therapy: Dilemma from a Psychiatric Point of View |
| title_sort | sarcoidosis and corticosteroid therapy dilemma from a psychiatric point of view |
| topic | R Medicine (General) RA Public aspects of medicine |
| url | https://eprints.ums.edu.my/id/eprint/26901/1/Sarcoidosis%20and%20Corticosteroid%20Therapy.pdf https://eprints.ums.edu.my/id/eprint/26901/2/Sarcoidosis%20and%20Corticosteroid%20Therapy1.pdf |
| work_keys_str_mv | AT mohdamiruddinmohdkassim sarcoidosisandcorticosteroidtherapydilemmafromapsychiatricpointofview AT ruzianamasiran sarcoidosisandcorticosteroidtherapydilemmafromapsychiatricpointofview AT pangnicholastzeping sarcoidosisandcorticosteroidtherapydilemmafromapsychiatricpointofview |