Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities
Phytochemicals of Christia vespertilionis plant is known for medicinal properties and used to treat various health problems. The present study revealed medicinal properties of the leaf extract of Christia vespertilionis plant as its total phenolic content derived is screened for their antioxidant, a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
AIP Publishing
2022
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/28936/1/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities.pdf https://eprints.ums.edu.my/id/eprint/28936/2/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities%20_ABSTRACT.pdf |
| _version_ | 1796910707509297152 |
|---|---|
| author | Adibah Bin Yamin Balam Satheesh Krishna Avula Vijaya Kumar Reddy Pasupuleti Visweswara Rao |
| author_facet | Adibah Bin Yamin Balam Satheesh Krishna Avula Vijaya Kumar Reddy Pasupuleti Visweswara Rao |
| author_sort | Adibah Bin Yamin |
| collection | UMS |
| description | Phytochemicals of Christia vespertilionis plant is known for medicinal properties and used to treat various health problems. The present study revealed medicinal properties of the leaf extract of Christia vespertilionis plant as its total phenolic content derived is screened for their antioxidant, antidiabetic and toxicity properties by Folin-Ciocalteu method, DPPH assay with butylated hydroxytoluene standard, a-amylase inhibition assay with metformin standard, brine shrimp lethality bioassay respectively. The total phenolic content of leaves extract is identified as 128.852±3.90mg gallic acid equivalent per gram of dried sample. The antioxidant potentiality is identified with 34.72-2.01 percentage of free radical scavenging against 200-6.25mg/mL concentrations with IC50 39.987mg/mL. The antidiabetic potentiality is identified with 23.33, 20.14 and 15.34 percentage against 500, 250 and 125mg/mL concentrations with IC50 35.2mg/mL. The percentage of mortality identified as 21.59-10.87% for 200 and 12.5mg/mL concentrations. The results revealed that Christia vespertilionis leaf extract is enriched with potential therapeutic properties of phenolic content that is associated with low toxicity levels. |
| first_indexed | 2024-03-06T03:08:16Z |
| format | Article |
| id | ums.eprints-28936 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:08:16Z |
| publishDate | 2022 |
| publisher | AIP Publishing |
| record_format | dspace |
| spelling | ums.eprints-289362022-07-28T04:15:29Z https://eprints.ums.edu.my/id/eprint/28936/ Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities Adibah Bin Yamin Balam Satheesh Krishna Avula Vijaya Kumar Reddy Pasupuleti Visweswara Rao RV1-431 Botanic, Thomsonian, and eclectic medicine Phytochemicals of Christia vespertilionis plant is known for medicinal properties and used to treat various health problems. The present study revealed medicinal properties of the leaf extract of Christia vespertilionis plant as its total phenolic content derived is screened for their antioxidant, antidiabetic and toxicity properties by Folin-Ciocalteu method, DPPH assay with butylated hydroxytoluene standard, a-amylase inhibition assay with metformin standard, brine shrimp lethality bioassay respectively. The total phenolic content of leaves extract is identified as 128.852±3.90mg gallic acid equivalent per gram of dried sample. The antioxidant potentiality is identified with 34.72-2.01 percentage of free radical scavenging against 200-6.25mg/mL concentrations with IC50 39.987mg/mL. The antidiabetic potentiality is identified with 23.33, 20.14 and 15.34 percentage against 500, 250 and 125mg/mL concentrations with IC50 35.2mg/mL. The percentage of mortality identified as 21.59-10.87% for 200 and 12.5mg/mL concentrations. The results revealed that Christia vespertilionis leaf extract is enriched with potential therapeutic properties of phenolic content that is associated with low toxicity levels. AIP Publishing 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/28936/1/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities.pdf text en https://eprints.ums.edu.my/id/eprint/28936/2/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities%20_ABSTRACT.pdf Adibah Bin Yamin and Balam Satheesh Krishna and Avula Vijaya Kumar Reddy and Pasupuleti Visweswara Rao (2022) Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities. AIP Publishing, 2390. pp. 1-5. ISSN 0094-243X https://aip.scitation.org/doi/pdf/10.1063/5.0068918 https://doi.org/10.1063/5.0068918 https://doi.org/10.1063/5.0068918 |
| spellingShingle | RV1-431 Botanic, Thomsonian, and eclectic medicine Adibah Bin Yamin Balam Satheesh Krishna Avula Vijaya Kumar Reddy Pasupuleti Visweswara Rao Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title | Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title_full | Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title_fullStr | Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title_full_unstemmed | Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title_short | Phytochemicals of Christia vespertilionis leaf extract: Antioxidant, antidiabetic and toxicity capabilities |
| title_sort | phytochemicals of christia vespertilionis leaf extract antioxidant antidiabetic and toxicity capabilities |
| topic | RV1-431 Botanic, Thomsonian, and eclectic medicine |
| url | https://eprints.ums.edu.my/id/eprint/28936/1/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities.pdf https://eprints.ums.edu.my/id/eprint/28936/2/Phytochemicals%20of%20Christia%20vespertilionis%20leaf%20extract_%20Antioxidant%2C%20antidiabetic%20and%20toxicity%20capabilities%20_ABSTRACT.pdf |
| work_keys_str_mv | AT adibahbinyamin phytochemicalsofchristiavespertilionisleafextractantioxidantantidiabeticandtoxicitycapabilities AT balamsatheeshkrishna phytochemicalsofchristiavespertilionisleafextractantioxidantantidiabeticandtoxicitycapabilities AT avulavijayakumarreddy phytochemicalsofchristiavespertilionisleafextractantioxidantantidiabeticandtoxicitycapabilities AT pasupuletivisweswararao phytochemicalsofchristiavespertilionisleafextractantioxidantantidiabeticandtoxicitycapabilities |