Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient
Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. Case Report: We report a case of a giant GIST (25×18×8.5...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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International Scientific Literature, Inc.
2022
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| Online Access: | https://eprints.ums.edu.my/id/eprint/28947/1/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient.pdf https://eprints.ums.edu.my/id/eprint/28947/2/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient%20_ABSTRACT.pdf |
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| author | Zhi, Bryan Yong Yeoh Vee, Chuan Hoe Shu, Ning Kong Wei, Kiat Ooi Kar, Yee Chiew Mohd Firdaus Mohd Hayati |
| author_facet | Zhi, Bryan Yong Yeoh Vee, Chuan Hoe Shu, Ning Kong Wei, Kiat Ooi Kar, Yee Chiew Mohd Firdaus Mohd Hayati |
| author_sort | Zhi, Bryan Yong Yeoh |
| collection | UMS |
| description | Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. Case Report: We report a case of a giant GIST (25×18×8.5 cm) in an 83-year-old woman, which we believe is the largest reported GIST, in Borneo, Malaysia. She presented with gradually increasing abdominal distension with occasional discomfort on movement for 1 month. Computed tomography revealed a large multilobulated enhancing mass measuring 10×20×22 cm with no clear plane with the posterior gastric wall, duodenum, and pancreas. We performed a distal gastrectomy and transverse colon segmentectomy, as the tumor was plastered to the mesentery of the transverse colon. Despite extensive surgery, she recovered well after surgery. Due to her advanced age and the tumor size, a tyrosine kinase inhibitor was not given owing to the possibility of adverse effects. Conclusions: The management of GIST is complicated, especially for a huge GIST with local invasion. Despite the benefits of a tyrosine kinase inhibitor, the role of surgery in managing GIST is crucial, especially for patients with huge tumor size, advanced age, and local complications from the tumor. |
| first_indexed | 2024-03-06T03:08:18Z |
| format | Article |
| id | ums.eprints-28947 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:08:18Z |
| publishDate | 2022 |
| publisher | International Scientific Literature, Inc. |
| record_format | dspace |
| spelling | ums.eprints-289472022-07-28T00:08:20Z https://eprints.ums.edu.my/id/eprint/28947/ Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient Zhi, Bryan Yong Yeoh Vee, Chuan Hoe Shu, Ning Kong Wei, Kiat Ooi Kar, Yee Chiew Mohd Firdaus Mohd Hayati RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. Case Report: We report a case of a giant GIST (25×18×8.5 cm) in an 83-year-old woman, which we believe is the largest reported GIST, in Borneo, Malaysia. She presented with gradually increasing abdominal distension with occasional discomfort on movement for 1 month. Computed tomography revealed a large multilobulated enhancing mass measuring 10×20×22 cm with no clear plane with the posterior gastric wall, duodenum, and pancreas. We performed a distal gastrectomy and transverse colon segmentectomy, as the tumor was plastered to the mesentery of the transverse colon. Despite extensive surgery, she recovered well after surgery. Due to her advanced age and the tumor size, a tyrosine kinase inhibitor was not given owing to the possibility of adverse effects. Conclusions: The management of GIST is complicated, especially for a huge GIST with local invasion. Despite the benefits of a tyrosine kinase inhibitor, the role of surgery in managing GIST is crucial, especially for patients with huge tumor size, advanced age, and local complications from the tumor. International Scientific Literature, Inc. 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/28947/1/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient.pdf text en https://eprints.ums.edu.my/id/eprint/28947/2/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient%20_ABSTRACT.pdf Zhi, Bryan Yong Yeoh and Vee, Chuan Hoe and Shu, Ning Kong and Wei, Kiat Ooi and Kar, Yee Chiew and Mohd Firdaus Mohd Hayati (2022) Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient. American Journal of Case Reports, 23. pp. 1-6. ISSN 1941-5923 https://amjcaserep.com/abstract/fig/idArt/934492/id/f2-amjcaserep-23-e934492 https://doi.org/10.12659/AJCR.934492 https://doi.org/10.12659/AJCR.934492 |
| spellingShingle | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens Zhi, Bryan Yong Yeoh Vee, Chuan Hoe Shu, Ning Kong Wei, Kiat Ooi Kar, Yee Chiew Mohd Firdaus Mohd Hayati Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title | Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title_full | Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title_fullStr | Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title_full_unstemmed | Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title_short | Successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| title_sort | successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient |
| topic | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens |
| url | https://eprints.ums.edu.my/id/eprint/28947/1/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient.pdf https://eprints.ums.edu.my/id/eprint/28947/2/Successful%20en%20bloc%20resection%20of%20complicated%20giant%20stomach%20gastrointestinal%20stromal%20tumor%20in%20an%20elderly%20patient%20_ABSTRACT.pdf |
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