Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate

The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal struct...

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Autores principales: M. K., Sabullah, S. A., Ahmad, M. Y., Shukor, A. J., Gansau, N. A., Shamaan, A., Khalid, Mohd Rosni Sulaiman
Formato: Artículo
Lenguaje:English
English
Publicado: Universiti Putra Malaysia 2017
Materias:
Acceso en línea:https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf
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author M. K., Sabullah
S. A., Ahmad
M. Y., Shukor
A. J., Gansau
N. A., Shamaan
A., Khalid
Mohd Rosni Sulaiman
author_facet M. K., Sabullah
S. A., Ahmad
M. Y., Shukor
A. J., Gansau
N. A., Shamaan
A., Khalid
Mohd Rosni Sulaiman
author_sort M. K., Sabullah
collection UMS
description The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4 , the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure.
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spelling ums.eprints-291652021-09-10T06:58:31Z https://eprints.ums.edu.my/id/eprint/29165/ Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate M. K., Sabullah S. A., Ahmad M. Y., Shukor A. J., Gansau N. A., Shamaan A., Khalid Mohd Rosni Sulaiman SH171-179 Diseases and adverse factors The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4 , the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. Universiti Putra Malaysia 2017 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf M. K., Sabullah and S. A., Ahmad and M. Y., Shukor and A. J., Gansau and N. A., Shamaan and A., Khalid and Mohd Rosni Sulaiman (2017) Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate. International Food Research Journal, 24. pp. 1314-1320. ISSN 2231-7546 http://www.ifrj.upm.edu.my/24%20(03)%202017/(56).pdf
spellingShingle SH171-179 Diseases and adverse factors
M. K., Sabullah
S. A., Ahmad
M. Y., Shukor
A. J., Gansau
N. A., Shamaan
A., Khalid
Mohd Rosni Sulaiman
Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title_full Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title_fullStr Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title_full_unstemmed Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title_short Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
title_sort alteration in morphological features of puntius javanicus liver exposed to copper sulfate
topic SH171-179 Diseases and adverse factors
url https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf
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