Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate
The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal struct...
Autores principales: | , , , , , , |
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Formato: | Artículo |
Lenguaje: | English English |
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Universiti Putra Malaysia
2017
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Acceso en línea: | https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf |
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author | M. K., Sabullah S. A., Ahmad M. Y., Shukor A. J., Gansau N. A., Shamaan A., Khalid Mohd Rosni Sulaiman |
author_facet | M. K., Sabullah S. A., Ahmad M. Y., Shukor A. J., Gansau N. A., Shamaan A., Khalid Mohd Rosni Sulaiman |
author_sort | M. K., Sabullah |
collection | UMS |
description | The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4 , the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. |
first_indexed | 2024-03-06T03:08:43Z |
format | Article |
id | ums.eprints-29165 |
institution | Universiti Malaysia Sabah |
language | English English |
last_indexed | 2024-03-06T03:08:43Z |
publishDate | 2017 |
publisher | Universiti Putra Malaysia |
record_format | dspace |
spelling | ums.eprints-291652021-09-10T06:58:31Z https://eprints.ums.edu.my/id/eprint/29165/ Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate M. K., Sabullah S. A., Ahmad M. Y., Shukor A. J., Gansau N. A., Shamaan A., Khalid Mohd Rosni Sulaiman SH171-179 Diseases and adverse factors The environmental toxicants such as copper are known to affect vital organ especially liver. This study examined the effects of copper sulfate (CuSO4 ) on the liver morphological structure of P. javanicus. The untreated control, 0.1 and 0.3 mg/L CuSO4 treated groups displayed normal polygonal structure of the hepatocyte. However, at the concentrations of 0.5, 1.0 and 5.0 mg/L CuSO4 , the hepatostructure was significantly affected, as shown by the increasing number of dilation and congestion of sinusoids, vacuolation, macrophage activities and peliosis. The damage level and HSI value were increased while the number of hepatic nuclei per mm2 was decreased with the increasing of copper concentration. In conclusion, this study shows that the degree of liver damage in P.javanicus is dependent to the dose exposure. Universiti Putra Malaysia 2017 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf M. K., Sabullah and S. A., Ahmad and M. Y., Shukor and A. J., Gansau and N. A., Shamaan and A., Khalid and Mohd Rosni Sulaiman (2017) Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate. International Food Research Journal, 24. pp. 1314-1320. ISSN 2231-7546 http://www.ifrj.upm.edu.my/24%20(03)%202017/(56).pdf |
spellingShingle | SH171-179 Diseases and adverse factors M. K., Sabullah S. A., Ahmad M. Y., Shukor A. J., Gansau N. A., Shamaan A., Khalid Mohd Rosni Sulaiman Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title_full | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title_fullStr | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title_full_unstemmed | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title_short | Alteration in morphological features of Puntius javanicus liver exposed to copper sulfate |
title_sort | alteration in morphological features of puntius javanicus liver exposed to copper sulfate |
topic | SH171-179 Diseases and adverse factors |
url | https://eprints.ums.edu.my/id/eprint/29165/1/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate%20ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/29165/3/Alteration%20in%20morphological%20features%20of%20Puntius%20javanicus%20liver%20exposed%20to%20copper%20sulfate.pdf |
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