Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause

Cirrhosis is the result of chronic liver disease due to a variety of causes. It is deemed to be cryptogenic when the leading cause cannot be identified despite extensive laboratory, radiological and pathological investigations. The prevalence of cryptogenic cirrhosis diagnosis has been dramatically...

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Main Authors: Alvin Oliver Payus, Justin Leow Wen Hsiang, Ong Hui Yun, Neeraj Vinayakumar
Format: Article
Language:English
English
Published: University of the Philippines Manila 2021
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/30762/1/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause-ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/30762/2/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause.pdf
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author Alvin Oliver Payus
Justin Leow Wen Hsiang
Ong Hui Yun
Neeraj Vinayakumar
author_facet Alvin Oliver Payus
Justin Leow Wen Hsiang
Ong Hui Yun
Neeraj Vinayakumar
author_sort Alvin Oliver Payus
collection UMS
description Cirrhosis is the result of chronic liver disease due to a variety of causes. It is deemed to be cryptogenic when the leading cause cannot be identified despite extensive laboratory, radiological and pathological investigations. The prevalence of cryptogenic cirrhosis diagnosis has been dramatically reduced in recent years due to the advanced achievement in diagnostic medicine, whereby it is attributed to only about less than 5% of cirrhosis cases. Here, we present a case of a 16-year-old boy with nonsignificant family history, was not taking any regular medication, and presented with progressive intermittent jaundice for a few years due to liver cirrhosis. Although an extensive investigation has been done, the etiology of the cirrhotic liver was still unknown. He had no features to support nonalcoholic steatohepatitis. He was in Child’s Grade B and prophylactically treated with a regular dose of propranolol to prevent portal hypertension complication while waiting for a liver transplant. This case report served the objective of showing that despite the advances in medical diagnostic techniques, cryptogenic cirrhosis is still used as a diagnosis in cases of chronic liver disease of unknown etiology.
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spelling ums.eprints-307622021-10-26T11:22:06Z https://eprints.ums.edu.my/id/eprint/30762/ Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause Alvin Oliver Payus Justin Leow Wen Hsiang Ong Hui Yun Neeraj Vinayakumar QM1-695 Human anatomy RC799-869 Diseases of the digestive system. Gastroenterology Cirrhosis is the result of chronic liver disease due to a variety of causes. It is deemed to be cryptogenic when the leading cause cannot be identified despite extensive laboratory, radiological and pathological investigations. The prevalence of cryptogenic cirrhosis diagnosis has been dramatically reduced in recent years due to the advanced achievement in diagnostic medicine, whereby it is attributed to only about less than 5% of cirrhosis cases. Here, we present a case of a 16-year-old boy with nonsignificant family history, was not taking any regular medication, and presented with progressive intermittent jaundice for a few years due to liver cirrhosis. Although an extensive investigation has been done, the etiology of the cirrhotic liver was still unknown. He had no features to support nonalcoholic steatohepatitis. He was in Child’s Grade B and prophylactically treated with a regular dose of propranolol to prevent portal hypertension complication while waiting for a liver transplant. This case report served the objective of showing that despite the advances in medical diagnostic techniques, cryptogenic cirrhosis is still used as a diagnosis in cases of chronic liver disease of unknown etiology. University of the Philippines Manila 2021-07-17 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/30762/1/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause-ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/30762/2/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause.pdf Alvin Oliver Payus and Justin Leow Wen Hsiang and Ong Hui Yun and Neeraj Vinayakumar (2021) Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause. Acta Medica Philippina. pp. 1-5. ISSN 2094-9278 https://actamedicaphilippina.upm.edu.ph/index.php/acta/article/view/1747 https://doi.org/10.47895/amp.vi0.1747 https://doi.org/10.47895/amp.vi0.1747
spellingShingle QM1-695 Human anatomy
RC799-869 Diseases of the digestive system. Gastroenterology
Alvin Oliver Payus
Justin Leow Wen Hsiang
Ong Hui Yun
Neeraj Vinayakumar
Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title_full Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title_fullStr Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title_full_unstemmed Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title_short Cryptogenic cirrhosis, an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
title_sort cryptogenic cirrhosis an ambiguity of a diagnosis a case report of progressive cirrhosis of undetermined cause
topic QM1-695 Human anatomy
RC799-869 Diseases of the digestive system. Gastroenterology
url https://eprints.ums.edu.my/id/eprint/30762/1/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause-ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/30762/2/Cryptogenic%20cirrhosis%2C%20an%20ambiguity%20of%20a%20diagnosis%20a%20case%20report%20of%20progressive%20cirrhosis%20of%20undetermined%20cause.pdf
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