Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia
Gastric cancer is an important cause of mortality in Sabah, Malaysia, but the prevalence of Helicobacter pylori infection in this state is unknown. Serology is an important tool for the surveillance of H. pylori infection. The objective of this study was to determine the prevalence of H. pylori infe...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English English |
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Elsevier Ltd
2021
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| Online Access: | https://eprints.ums.edu.my/id/eprint/31874/1/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/31874/2/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.pdf |
| _version_ | 1825714589465051136 |
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| author | Daisuke Mori Jecelyn Leaslie John Shahnaz Irwani Sabri Saliz Mazrina Shaharom Hidekatsu Iha Yoshio Yamaoka Takashi Matsumoto Kamruddin Ahmed |
| author_facet | Daisuke Mori Jecelyn Leaslie John Shahnaz Irwani Sabri Saliz Mazrina Shaharom Hidekatsu Iha Yoshio Yamaoka Takashi Matsumoto Kamruddin Ahmed |
| author_sort | Daisuke Mori |
| collection | UMS |
| description | Gastric cancer is an important cause of mortality in Sabah, Malaysia, but the prevalence of Helicobacter pylori infection in this state is unknown. Serology is an important tool for the surveillance of H. pylori infection. The objective of this study was to determine the prevalence of H. pylori infection by serology, and to provide information for policy discussions on H. pylori control programmes in Sabah. Methods: This cross-sectional study analysed serum samples collected from blood donors in a hospital in Kota Kinabalu, Sabah. H. pylori antibody concentration was measured using a commercially available kit. Results: The prevalence of H. pylori was 28.4% (204/718), and the infection rate was highest in subjects aged 30–39 years. Men were more likely to be infected than women. The H. pylori infection rate was highest among those of Kadazan (19.1%) ethnicity, followed by Dusun (15.7%), Bajau (14.7%) and Rungus (10.8%). Binary logistic regression analysis indicated that Chinese ( P = 0.026) and Malay ( P = 0.035) ethnicities were protective against H. pylori infection compared with other ethnicities. Conclusions: The seropositivity rate of H. pylori in this study was similar to the overall seropositivity rate in Malaysia; however, Chinese and Malay ethnicities were found to be protective against H. pylori infection. |
| first_indexed | 2024-03-06T03:14:04Z |
| format | Article |
| id | ums.eprints-31874 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:14:04Z |
| publishDate | 2021 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | ums.eprints-318742022-03-17T04:27:20Z https://eprints.ums.edu.my/id/eprint/31874/ Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia Daisuke Mori Jecelyn Leaslie John Shahnaz Irwani Sabri Saliz Mazrina Shaharom Hidekatsu Iha Yoshio Yamaoka Takashi Matsumoto Kamruddin Ahmed RA421-790.95 Public health. Hygiene. Preventive medicine Gastric cancer is an important cause of mortality in Sabah, Malaysia, but the prevalence of Helicobacter pylori infection in this state is unknown. Serology is an important tool for the surveillance of H. pylori infection. The objective of this study was to determine the prevalence of H. pylori infection by serology, and to provide information for policy discussions on H. pylori control programmes in Sabah. Methods: This cross-sectional study analysed serum samples collected from blood donors in a hospital in Kota Kinabalu, Sabah. H. pylori antibody concentration was measured using a commercially available kit. Results: The prevalence of H. pylori was 28.4% (204/718), and the infection rate was highest in subjects aged 30–39 years. Men were more likely to be infected than women. The H. pylori infection rate was highest among those of Kadazan (19.1%) ethnicity, followed by Dusun (15.7%), Bajau (14.7%) and Rungus (10.8%). Binary logistic regression analysis indicated that Chinese ( P = 0.026) and Malay ( P = 0.035) ethnicities were protective against H. pylori infection compared with other ethnicities. Conclusions: The seropositivity rate of H. pylori in this study was similar to the overall seropositivity rate in Malaysia; however, Chinese and Malay ethnicities were found to be protective against H. pylori infection. Elsevier Ltd 2021-12-26 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/31874/1/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/31874/2/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.pdf Daisuke Mori and Jecelyn Leaslie John and Shahnaz Irwani Sabri and Saliz Mazrina Shaharom and Hidekatsu Iha and Yoshio Yamaoka and Takashi Matsumoto and Kamruddin Ahmed (2021) Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia. IJID Regions, 2. pp. 126-129. ISSN 2772-7076 https://www-sciencedirect-com.ezproxy.ums.edu.my/science/article/pii/S2772707622000029 https://doi.org/10.1016/j.ijregi.2021.12.012 https://doi.org/10.1016/j.ijregi.2021.12.012 |
| spellingShingle | RA421-790.95 Public health. Hygiene. Preventive medicine Daisuke Mori Jecelyn Leaslie John Shahnaz Irwani Sabri Saliz Mazrina Shaharom Hidekatsu Iha Yoshio Yamaoka Takashi Matsumoto Kamruddin Ahmed Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title | Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title_full | Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title_fullStr | Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title_full_unstemmed | Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title_short | Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia |
| title_sort | seroepidemiological survey of the prevalence of helicobacter pylori infection in sabah malaysia |
| topic | RA421-790.95 Public health. Hygiene. Preventive medicine |
| url | https://eprints.ums.edu.my/id/eprint/31874/1/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/31874/2/Seroepidemiological%20survey%20of%20the%20prevalence%20of%20Helicobacter%20pylori%20infection%20in%20Sabah%2C%20Malaysia.pdf |
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