Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of b-Glucuronidase and in silico study
New benzimidazole analogues (1–18) were synthesized and characterized through differ- ent spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for b-glucuronidase inhibitory potential. All analogues showed varied degree of inhibitory potentials with IC50 values r...
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