A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia

This study outlines and developed a multilayer perceptron (MLP) neural network model for adolescent hypertension classification focusing on the use of simple anthropometric and sociodemographic data collected from a cross-sectional research study in Sarawak, Malaysia. Among the 2,461 data collected,...

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Main Authors: Chai, Soo See, Cheah, Whye Lian, Kok, Luong Goh, Chang, Robin Yee Hui, Kwan, Yong Sim, Chin, Kim On
Format: Article
Language:English
English
Published: Hindawi Publishing Corporation 2021
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Online Access:https://eprints.ums.edu.my/id/eprint/32830/1/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements.pdf
https://eprints.ums.edu.my/id/eprint/32830/2/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements1.pdf
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author Chai, Soo See
Cheah, Whye Lian
Kok, Luong Goh
Chang, Robin Yee Hui
Kwan, Yong Sim
Chin, Kim On
author_facet Chai, Soo See
Cheah, Whye Lian
Kok, Luong Goh
Chang, Robin Yee Hui
Kwan, Yong Sim
Chin, Kim On
author_sort Chai, Soo See
collection UMS
description This study outlines and developed a multilayer perceptron (MLP) neural network model for adolescent hypertension classification focusing on the use of simple anthropometric and sociodemographic data collected from a cross-sectional research study in Sarawak, Malaysia. Among the 2,461 data collected, 741 were hypertensive (30.1%) and 1720 were normal (69.9%). During the data gathering process, eleven anthropometric measurements and sociodemographic data were collected. The variable selection procedure in the methodology proposed selected five parameters: weight, weight-to-height ratio (WHtR), age, sex, and ethnicity, as the input of the network model. The developed MLP model with a single hidden layer of 50 hidden neurons managed to achieve a sensitivity of 0.41, specificity of 0.91, precision of 0.65, F-score of 0.50, accuracy of 0.76, and Area Under the Receiver Operating Characteristic (ROC) Curve (AUC) of 0.75 using the imbalanced data set. Analyzing the performance metrics obtained from the training, validation and testing data sets show that the developed network model is well-generalized. Using Bayes’ Theorem, an adolescent classified as hypertensive using this created model has a 66.2% likelihood of having hypertension in the Sarawak adolescent population, which has a hypertension prevalence of 30.1%. When the prevalence of hypertension in the Sarawak population was increased to 50%, the developed model could predict an adolescent having hypertension with an 82.0% chance, whereas when the prevalence of hypertension was reduced to 10%, the developed model could only predict true positive hypertension with a 33.6% chance. With the sensitivity of the model increasing to 65% and 90% while retaining a specificity of 91%, the true positivity of an adolescent being hypertension would be 75.7% and 81.2%, respectively, according to Bayes’ Theorem. The findings show that simple anthropometric measurements paired with sociodemographic data are feasible to be used to classify hypertension in adolescents using the developed MLP model in Sarawak adolescent population with modest hypertension prevalence. However, a model with higher sensitivity and specificity is required for better positive hypertension predictive value when the prevalence is low. We conclude that the developed classification model could serve as a quick and easy preliminary warning tool for screening high-risk adolescents of developing hypertension.
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spelling ums.eprints-328302022-06-16T08:08:57Z https://eprints.ums.edu.my/id/eprint/32830/ A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia Chai, Soo See Cheah, Whye Lian Kok, Luong Goh Chang, Robin Yee Hui Kwan, Yong Sim Chin, Kim On QA75.5-76.95 Electronic computers. Computer science This study outlines and developed a multilayer perceptron (MLP) neural network model for adolescent hypertension classification focusing on the use of simple anthropometric and sociodemographic data collected from a cross-sectional research study in Sarawak, Malaysia. Among the 2,461 data collected, 741 were hypertensive (30.1%) and 1720 were normal (69.9%). During the data gathering process, eleven anthropometric measurements and sociodemographic data were collected. The variable selection procedure in the methodology proposed selected five parameters: weight, weight-to-height ratio (WHtR), age, sex, and ethnicity, as the input of the network model. The developed MLP model with a single hidden layer of 50 hidden neurons managed to achieve a sensitivity of 0.41, specificity of 0.91, precision of 0.65, F-score of 0.50, accuracy of 0.76, and Area Under the Receiver Operating Characteristic (ROC) Curve (AUC) of 0.75 using the imbalanced data set. Analyzing the performance metrics obtained from the training, validation and testing data sets show that the developed network model is well-generalized. Using Bayes’ Theorem, an adolescent classified as hypertensive using this created model has a 66.2% likelihood of having hypertension in the Sarawak adolescent population, which has a hypertension prevalence of 30.1%. When the prevalence of hypertension in the Sarawak population was increased to 50%, the developed model could predict an adolescent having hypertension with an 82.0% chance, whereas when the prevalence of hypertension was reduced to 10%, the developed model could only predict true positive hypertension with a 33.6% chance. With the sensitivity of the model increasing to 65% and 90% while retaining a specificity of 91%, the true positivity of an adolescent being hypertension would be 75.7% and 81.2%, respectively, according to Bayes’ Theorem. The findings show that simple anthropometric measurements paired with sociodemographic data are feasible to be used to classify hypertension in adolescents using the developed MLP model in Sarawak adolescent population with modest hypertension prevalence. However, a model with higher sensitivity and specificity is required for better positive hypertension predictive value when the prevalence is low. We conclude that the developed classification model could serve as a quick and easy preliminary warning tool for screening high-risk adolescents of developing hypertension. Hindawi Publishing Corporation 2021 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/32830/1/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements.pdf text en https://eprints.ums.edu.my/id/eprint/32830/2/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements1.pdf Chai, Soo See and Cheah, Whye Lian and Kok, Luong Goh and Chang, Robin Yee Hui and Kwan, Yong Sim and Chin, Kim On (2021) A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia. Computational and Mathematical Methods in Medicine, 2021. pp. 1-11. ISSN 0953-0460 https://www.hindawi.com/journals/cmmm/2021/2794888/ https://doi.org/10.1155/2021/2794888 https://doi.org/10.1155/2021/2794888
spellingShingle QA75.5-76.95 Electronic computers. Computer science
Chai, Soo See
Cheah, Whye Lian
Kok, Luong Goh
Chang, Robin Yee Hui
Kwan, Yong Sim
Chin, Kim On
A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title_full A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title_fullStr A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title_full_unstemmed A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title_short A Multilayer Perceptron Neural Network Model to Classify Hypertension in Adolescents Using Anthropometric Measurements: A Cross-Sectional Study in Sarawak, Malaysia
title_sort multilayer perceptron neural network model to classify hypertension in adolescents using anthropometric measurements a cross sectional study in sarawak malaysia
topic QA75.5-76.95 Electronic computers. Computer science
url https://eprints.ums.edu.my/id/eprint/32830/1/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements.pdf
https://eprints.ums.edu.my/id/eprint/32830/2/A%20Multilayer%20Perceptron%20Neural%20Network%20Model%20to%20Classify%20Hypertension%20in%20Adolescents%20Using%20Anthropometric%20Measurements1.pdf
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