Development of nanoparticles for pharmaceutical preparations using supercritical techniques
This review focuses on nanoparticle (NP) synthesis and particle size design using supercritical fluid (SCF) technology for pharmaceutical formulations. SCF technology is seen as a pioneering step forward in particle size design, and also plays a critical role in addressing the problem of residual so...
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Taylor & Francis
2022
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Online Access: | https://eprints.ums.edu.my/id/eprint/33299/1/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques.pdf https://eprints.ums.edu.my/id/eprint/33299/2/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques1.pdf |
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author | Tariqul Islam Abdullah Al Ragib Sahena Ferdosh A. B. M. Helal Uddin Md. Jahurul Haque Akanda e Md. Abdur Rashid Mia Reddy Prasad D. M Yunus Kamaruzzaman Md. Zaidul Islam Sarker |
author_facet | Tariqul Islam Abdullah Al Ragib Sahena Ferdosh A. B. M. Helal Uddin Md. Jahurul Haque Akanda e Md. Abdur Rashid Mia Reddy Prasad D. M Yunus Kamaruzzaman Md. Zaidul Islam Sarker |
author_sort | Tariqul Islam |
collection | UMS |
description | This review focuses on nanoparticle (NP) synthesis and particle size design using supercritical fluid (SCF) technology for pharmaceutical formulations. SCF technology is seen as a pioneering step forward in particle size design, and also plays a critical role in addressing the problem of residual solvents in pharmaceutical and biomedical research. In SCF technology, one of the most important components is environmentally friendly supercritical CO2 (scCO2) fluid, which is very common and cost-effective because nontoxic green technology is used for the formation of nanomedicine in drug delivery. In the case of pharmaceutical science, numerous complex procedures are required in order to manufacture NPs. The working principles of the rapid expansion of supercritical solutions (RESS), supercritical antisolvent (SAS), supercritical fluid extraction of emulsions (SFEE), solution-enhanced dispersion by supercritical fluids (SEDS), rapid expansion of supercritical solution into a liquid solvent (RESOLV), and particles from gas-saturated solution (PGSS) are widely used throughout the industry. Most of the supercritical (SC) approaches (total 23 methods) including the newly established methods are cited in this manuscript. This study offers a detailed overview of fundamental principles and relevant roles, advantages, and difficulties in the creation of SCF methods for the formation of NPs. It gives the clear concept to select the proper method, solvent, active ingredients, and polymers in NP preparation. |
first_indexed | 2024-03-06T03:17:58Z |
format | Article |
id | ums.eprints-33299 |
institution | Universiti Malaysia Sabah |
language | English English |
last_indexed | 2024-03-06T03:17:58Z |
publishDate | 2022 |
publisher | Taylor & Francis |
record_format | dspace |
spelling | ums.eprints-332992022-07-17T01:55:08Z https://eprints.ums.edu.my/id/eprint/33299/ Development of nanoparticles for pharmaceutical preparations using supercritical techniques Tariqul Islam Abdullah Al Ragib Sahena Ferdosh A. B. M. Helal Uddin Md. Jahurul Haque Akanda e Md. Abdur Rashid Mia Reddy Prasad D. M Yunus Kamaruzzaman Md. Zaidul Islam Sarker RM1-950 Therapeutics. Pharmacology This review focuses on nanoparticle (NP) synthesis and particle size design using supercritical fluid (SCF) technology for pharmaceutical formulations. SCF technology is seen as a pioneering step forward in particle size design, and also plays a critical role in addressing the problem of residual solvents in pharmaceutical and biomedical research. In SCF technology, one of the most important components is environmentally friendly supercritical CO2 (scCO2) fluid, which is very common and cost-effective because nontoxic green technology is used for the formation of nanomedicine in drug delivery. In the case of pharmaceutical science, numerous complex procedures are required in order to manufacture NPs. The working principles of the rapid expansion of supercritical solutions (RESS), supercritical antisolvent (SAS), supercritical fluid extraction of emulsions (SFEE), solution-enhanced dispersion by supercritical fluids (SEDS), rapid expansion of supercritical solution into a liquid solvent (RESOLV), and particles from gas-saturated solution (PGSS) are widely used throughout the industry. Most of the supercritical (SC) approaches (total 23 methods) including the newly established methods are cited in this manuscript. This study offers a detailed overview of fundamental principles and relevant roles, advantages, and difficulties in the creation of SCF methods for the formation of NPs. It gives the clear concept to select the proper method, solvent, active ingredients, and polymers in NP preparation. Taylor & Francis 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/33299/1/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques.pdf text en https://eprints.ums.edu.my/id/eprint/33299/2/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques1.pdf Tariqul Islam and Abdullah Al Ragib and Sahena Ferdosh and A. B. M. Helal Uddin and Md. Jahurul Haque Akanda e and Md. Abdur Rashid Mia and Reddy Prasad D. M and Yunus Kamaruzzaman and Md. Zaidul Islam Sarker (2022) Development of nanoparticles for pharmaceutical preparations using supercritical techniques. Chemical Engineering Communications. pp. 1-22. ISSN 0098-6445 https://www.tandfonline.com/doi/full/10.1080/00986445.2021.1983545 https://doi.org/10.1080/00986445.2021.1983545 https://doi.org/10.1080/00986445.2021.1983545 |
spellingShingle | RM1-950 Therapeutics. Pharmacology Tariqul Islam Abdullah Al Ragib Sahena Ferdosh A. B. M. Helal Uddin Md. Jahurul Haque Akanda e Md. Abdur Rashid Mia Reddy Prasad D. M Yunus Kamaruzzaman Md. Zaidul Islam Sarker Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title | Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title_full | Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title_fullStr | Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title_full_unstemmed | Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title_short | Development of nanoparticles for pharmaceutical preparations using supercritical techniques |
title_sort | development of nanoparticles for pharmaceutical preparations using supercritical techniques |
topic | RM1-950 Therapeutics. Pharmacology |
url | https://eprints.ums.edu.my/id/eprint/33299/1/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques.pdf https://eprints.ums.edu.my/id/eprint/33299/2/Development%20of%20nanoparticles%20for%20pharmaceutical%20preparations%20using%20supercritical%20techniques1.pdf |
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