Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge

Background: Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. Case presentation: We...

Full description

Bibliographic Details
Main Authors: Stacy A. Jamarun, Wong, Eugene Hung Chih
Format: Article
Language:English
English
Published: Elsevier Ltd 2022
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/33444/1/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis.pdf
https://eprints.ums.edu.my/id/eprint/33444/2/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis2.pdf
_version_ 1825714879539970048
author Stacy A. Jamarun
Wong, Eugene Hung Chih
author_facet Stacy A. Jamarun
Wong, Eugene Hung Chih
author_sort Stacy A. Jamarun
collection UMS
description Background: Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. Case presentation: We described a 72-year-old gentleman who presented with left-sided nasal obstruction, rhinorrhea and hyposmia and right-sided hearing loss. Examination revealed bilateral intranasal polyposis with right lobular swelling at torus tubarius and right sided middle ear effusion. Biopsy revealed inflammatory nasal polyps with nasopharyngeal amyloidosis. Patient was treated successfully with functional endoscopic sinus surgery (FESS) for nasal polyposis and an en bloc wide local excision of the torus tubarius with no signs of recurrence at one year follow-up. Conclusion: Clinicians should have raised index of suspicion of a possible primary nasopharyngeal amyloidosis in patients presenting with nasopharyngeal mass with co-existing nasal polyposis to avoid delay in diagnosis and treatment.
first_indexed 2024-03-06T03:18:19Z
format Article
id ums.eprints-33444
institution Universiti Malaysia Sabah
language English
English
last_indexed 2024-03-06T03:18:19Z
publishDate 2022
publisher Elsevier Ltd
record_format dspace
spelling ums.eprints-334442022-07-21T04:03:33Z https://eprints.ums.edu.my/id/eprint/33444/ Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge Stacy A. Jamarun Wong, Eugene Hung Chih RF341-437 Rhinology. Diseases of the nose, accessory sinuses, and nasopharynx Background: Primary nasopharyngeal amyloidosis is a rare entity of localised amyloidosis. Patients usually present with symptoms that mimic other common nasal diseases. We report an unusual case of nasopharyngeal amyloidosis that co-exist with nasal polyposis at the same time. Case presentation: We described a 72-year-old gentleman who presented with left-sided nasal obstruction, rhinorrhea and hyposmia and right-sided hearing loss. Examination revealed bilateral intranasal polyposis with right lobular swelling at torus tubarius and right sided middle ear effusion. Biopsy revealed inflammatory nasal polyps with nasopharyngeal amyloidosis. Patient was treated successfully with functional endoscopic sinus surgery (FESS) for nasal polyposis and an en bloc wide local excision of the torus tubarius with no signs of recurrence at one year follow-up. Conclusion: Clinicians should have raised index of suspicion of a possible primary nasopharyngeal amyloidosis in patients presenting with nasopharyngeal mass with co-existing nasal polyposis to avoid delay in diagnosis and treatment. Elsevier Ltd 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/33444/1/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis.pdf text en https://eprints.ums.edu.my/id/eprint/33444/2/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis2.pdf Stacy A. Jamarun and Wong, Eugene Hung Chih (2022) Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge. International Journal of Surgery Case Reports, 94 (107056). pp. 1-3. ISSN 2210-2612 https://www.sciencedirect.com/science/article/pii/S2210261222003029?via%3Dihub https://doi.org/10.1016/j.ijscr.2022.107056 https://doi.org/10.1016/j.ijscr.2022.107056
spellingShingle RF341-437 Rhinology. Diseases of the nose, accessory sinuses, and nasopharynx
Stacy A. Jamarun
Wong, Eugene Hung Chih
Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title_full Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title_fullStr Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title_full_unstemmed Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title_short Primary nasopharyngeal amyloidosis with nasal polyposis: Case report of a diagnostic challenge
title_sort primary nasopharyngeal amyloidosis with nasal polyposis case report of a diagnostic challenge
topic RF341-437 Rhinology. Diseases of the nose, accessory sinuses, and nasopharynx
url https://eprints.ums.edu.my/id/eprint/33444/1/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis.pdf
https://eprints.ums.edu.my/id/eprint/33444/2/Primary%20nasopharyngeal%20amyloidosis%20with%20nasal%20polyposis2.pdf
work_keys_str_mv AT stacyajamarun primarynasopharyngealamyloidosiswithnasalpolyposiscasereportofadiagnosticchallenge
AT wongeugenehungchih primarynasopharyngealamyloidosiswithnasalpolyposiscasereportofadiagnosticchallenge