Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy
Goblet cell carcinoid (GCC) is an enigmatic and rare tumour involving the appendix almost exclusively. It is a rare, aggressive subtype of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We herein highlight a 56-year-old lady with GCC wh...
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| Format: | Article |
| Language: | English English |
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Gazi Universitesi
2022
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| Online Access: | https://eprints.ums.edu.my/id/eprint/34232/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34232/2/ABSTRACT.pdf |
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| author | Rosli Ismail Mohd Firdaus Che Ani Salahuddin Baharom Nornazirah Azizan Andee Dzulkarnaen Zakaria Mohd Firdaus Mohd Hayati |
| author_facet | Rosli Ismail Mohd Firdaus Che Ani Salahuddin Baharom Nornazirah Azizan Andee Dzulkarnaen Zakaria Mohd Firdaus Mohd Hayati |
| author_sort | Rosli Ismail |
| collection | UMS |
| description | Goblet cell carcinoid (GCC) is an enigmatic and rare tumour involving the appendix almost exclusively. It is a rare, aggressive subtype of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We herein highlight a 56-year-old lady with GCC whom she presented initially with a typical presentation of acute appendicitis. The histologic hallmark of this entity is the presence of clusters of goblet cells in the lamina propria or submucosa stain for various neuroendocrine markers, though the intensity is often patchy. GCC of the appendix is rare and challenging. In advanced form, it can present with carcinoid symptoms but occasionally mimics classical presentations of acute appendicitis. A tumour measuring less than 1 cm and located at the tip of the appendix is sufficient for a simple appendicectomy which warrants a promising prognosis. |
| first_indexed | 2024-03-06T03:20:24Z |
| format | Article |
| id | ums.eprints-34232 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:20:24Z |
| publishDate | 2022 |
| publisher | Gazi Universitesi |
| record_format | dspace |
| spelling | ums.eprints-342322022-09-29T03:16:20Z https://eprints.ums.edu.my/id/eprint/34232/ Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy Rosli Ismail Mohd Firdaus Che Ani Salahuddin Baharom Nornazirah Azizan Andee Dzulkarnaen Zakaria Mohd Firdaus Mohd Hayati RD520-599.5 Surgery by region, system, or organ Goblet cell carcinoid (GCC) is an enigmatic and rare tumour involving the appendix almost exclusively. It is a rare, aggressive subtype of appendiceal tumours with neuroendocrine features, and controversy exists with regards to therapeutic strategy. We herein highlight a 56-year-old lady with GCC whom she presented initially with a typical presentation of acute appendicitis. The histologic hallmark of this entity is the presence of clusters of goblet cells in the lamina propria or submucosa stain for various neuroendocrine markers, though the intensity is often patchy. GCC of the appendix is rare and challenging. In advanced form, it can present with carcinoid symptoms but occasionally mimics classical presentations of acute appendicitis. A tumour measuring less than 1 cm and located at the tip of the appendix is sufficient for a simple appendicectomy which warrants a promising prognosis. Gazi Universitesi 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34232/1/FULL%20TEXT.pdf text en https://eprints.ums.edu.my/id/eprint/34232/2/ABSTRACT.pdf Rosli Ismail and Mohd Firdaus Che Ani and Salahuddin Baharom and Nornazirah Azizan and Andee Dzulkarnaen Zakaria and Mohd Firdaus Mohd Hayati (2022) Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy. Gazi Medical Journal, 33 (4). pp. 423-425. ISSN 2147-2092 https://medicaljournal.gazi.edu.tr/index.php/GMJ/article/view/3507/2624 http://dx.doi.org/10.12996/gmj.2022.96 http://dx.doi.org/10.12996/gmj.2022.96 |
| spellingShingle | RD520-599.5 Surgery by region, system, or organ Rosli Ismail Mohd Firdaus Che Ani Salahuddin Baharom Nornazirah Azizan Andee Dzulkarnaen Zakaria Mohd Firdaus Mohd Hayati Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title | Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title_full | Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title_fullStr | Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title_full_unstemmed | Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title_short | Appendiceal Goblet Cell Carcinoid: An Unexpected Histology Following Simple Appendicectomy |
| title_sort | appendiceal goblet cell carcinoid an unexpected histology following simple appendicectomy |
| topic | RD520-599.5 Surgery by region, system, or organ |
| url | https://eprints.ums.edu.my/id/eprint/34232/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34232/2/ABSTRACT.pdf |
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