Obesity and prolactin in various populations
Association of Obesity with altered levels of serum prolactin (PRL), a marker of stress is well documented. The objective of this systematic review and meta-analysis was to estimate the association between obesity and PRL according to sex, ethnicity and age. PubMed, Web of Science (WoS) & EBSCO...
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| Format: | Article |
| Language: | English English |
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Institute of Medico-Legal Publications
2019
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| Online Access: | https://eprints.ums.edu.my/id/eprint/34738/2/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34738/1/ABSTRACT.pdf |
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| author | Jaiprakash Mohanraj Urban John Arnold D' Souza Heethal Jaiprakash Fong, Alison Siat Yee |
| author_facet | Jaiprakash Mohanraj Urban John Arnold D' Souza Heethal Jaiprakash Fong, Alison Siat Yee |
| author_sort | Jaiprakash Mohanraj |
| collection | UMS |
| description | Association of Obesity with altered levels of serum prolactin (PRL), a marker of stress is well documented. The objective of this systematic review and meta-analysis was to estimate the association between obesity and PRL according to sex, ethnicity and age. PubMed, Web of Science (WoS) & EBSCO database were searched from the 5th to 20th of October 2018. Two reviewers independently extracted data from 12 cross sectional studies that used body mass index (BMI), waist circumference (WC) or waist-to-hip ratio (WHR) as measures of obesity and aggregated using the random-effect model. The correlation (r) for BMI and PRL was -0.231; 95% confidence interval (CI) = -0.392 to -0.055) in adults and (r = -0.500; 95% CI = -0.622 to -0.354) in children. In adults, r for BMI and PRL was greater in women than men by -0.127 (95% CI = -0.178 to -0.05) and greater in European populations r=0.156 (95% CI = -0132 to -0.079) than Middle Eastern populations r = -0.655(95% CI = -0.880 to 0.191). Obesity is associated with decreased levels of PRL, and the association is greater among women and Europeans. The emergence of difference between different genders was observed only in adulthood. |
| first_indexed | 2024-03-06T03:21:48Z |
| format | Article |
| id | ums.eprints-34738 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:21:48Z |
| publishDate | 2019 |
| publisher | Institute of Medico-Legal Publications |
| record_format | dspace |
| spelling | ums.eprints-347382022-11-08T04:13:02Z https://eprints.ums.edu.my/id/eprint/34738/ Obesity and prolactin in various populations Jaiprakash Mohanraj Urban John Arnold D' Souza Heethal Jaiprakash Fong, Alison Siat Yee RA421-790.95 Public health. Hygiene. Preventive medicine Association of Obesity with altered levels of serum prolactin (PRL), a marker of stress is well documented. The objective of this systematic review and meta-analysis was to estimate the association between obesity and PRL according to sex, ethnicity and age. PubMed, Web of Science (WoS) & EBSCO database were searched from the 5th to 20th of October 2018. Two reviewers independently extracted data from 12 cross sectional studies that used body mass index (BMI), waist circumference (WC) or waist-to-hip ratio (WHR) as measures of obesity and aggregated using the random-effect model. The correlation (r) for BMI and PRL was -0.231; 95% confidence interval (CI) = -0.392 to -0.055) in adults and (r = -0.500; 95% CI = -0.622 to -0.354) in children. In adults, r for BMI and PRL was greater in women than men by -0.127 (95% CI = -0.178 to -0.05) and greater in European populations r=0.156 (95% CI = -0132 to -0.079) than Middle Eastern populations r = -0.655(95% CI = -0.880 to 0.191). Obesity is associated with decreased levels of PRL, and the association is greater among women and Europeans. The emergence of difference between different genders was observed only in adulthood. Institute of Medico-Legal Publications 2019 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34738/2/FULL%20TEXT.pdf text en https://eprints.ums.edu.my/id/eprint/34738/1/ABSTRACT.pdf Jaiprakash Mohanraj and Urban John Arnold D' Souza and Heethal Jaiprakash and Fong, Alison Siat Yee (2019) Obesity and prolactin in various populations. Indian Journal of Public Health Research & Development, 10. pp. 1351-1356. ISSN 0976-0245 (P-ISSN) , 0976-5506 (E-ISSN) https://ijphrd.com/scripts/IJPHRD%20June%202019.pdf https://doi.org/10.5958/0976-5506.2019.01485.2 https://doi.org/10.5958/0976-5506.2019.01485.2 |
| spellingShingle | RA421-790.95 Public health. Hygiene. Preventive medicine Jaiprakash Mohanraj Urban John Arnold D' Souza Heethal Jaiprakash Fong, Alison Siat Yee Obesity and prolactin in various populations |
| title | Obesity and prolactin in various populations |
| title_full | Obesity and prolactin in various populations |
| title_fullStr | Obesity and prolactin in various populations |
| title_full_unstemmed | Obesity and prolactin in various populations |
| title_short | Obesity and prolactin in various populations |
| title_sort | obesity and prolactin in various populations |
| topic | RA421-790.95 Public health. Hygiene. Preventive medicine |
| url | https://eprints.ums.edu.my/id/eprint/34738/2/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34738/1/ABSTRACT.pdf |
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