Covid-19 vaccine and its consequences in pregnancy: Brief review
Pregnancy is linked to a higher incidence of severe Covid-19. It’s critical to find safe vaccinations that elicit protective pregnant and fetal immune responses. This review summarises the rate of COVID-19 infection, maternal antibodies responsiveness, placenta antibody transmission, and adverse eve...
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| Format: | Article |
| Language: | English English |
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Elsevier Ltd
2021
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| Online Access: | https://eprints.ums.edu.my/id/eprint/34942/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34942/2/FULLTEXT.pdf |
| _version_ | 1796911689706242048 |
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| author | Nang, Kham Oo Leik Fatimah Ahmedy Rhanye Mac Guad Dg Marshitah Pg Baharuddin |
| author_facet | Nang, Kham Oo Leik Fatimah Ahmedy Rhanye Mac Guad Dg Marshitah Pg Baharuddin |
| author_sort | Nang, Kham Oo Leik |
| collection | UMS |
| description | Pregnancy is linked to a higher incidence of severe Covid-19. It’s critical to find safe vaccinations that elicit protective pregnant and fetal immune responses. This review summarises the rate of COVID-19 infection, maternal antibodies responsiveness, placenta antibody transmission, and adverse events after COVID-19 vaccination in pregnancy studied in epidemiological studies evaluating mRNA vaccines. Potential COVID-19 infection in pregnant women can be prevented using mRNA-based vaccinations. Gestation, childbirth, and perinatal mortality were proven unaffected by COVID-19 vaccination. Injection-site discomfort, tiredness, and migraine are the most prevalent side effects, but these are temporary. After the first dosage of vaccinations, fast antibody responses were demonstrated. The adaptive immunity is found to be more significant after booster vaccination, and is linked to improved placental antigen transmission. Two vaccination doses are associated with more robust maternal and fetal antibody levels. Longer delays between the first immunization dosage and birth are linked to greater fetal IgG antibody levels with reduction in antigen transmission proportion. The mRNA vacciness are effective in reducing the severity of COVID-19 infection and these vaccinations are regarded to be safe options for pregnant women and their unborn fetus. |
| first_indexed | 2024-03-06T03:22:24Z |
| format | Article |
| id | ums.eprints-34942 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:22:24Z |
| publishDate | 2021 |
| publisher | Elsevier Ltd |
| record_format | dspace |
| spelling | ums.eprints-349422022-11-22T03:49:54Z https://eprints.ums.edu.my/id/eprint/34942/ Covid-19 vaccine and its consequences in pregnancy: Brief review Nang, Kham Oo Leik Fatimah Ahmedy Rhanye Mac Guad Dg Marshitah Pg Baharuddin QR75-99.5 Bacteria RG551-591 Pregnancy Pregnancy is linked to a higher incidence of severe Covid-19. It’s critical to find safe vaccinations that elicit protective pregnant and fetal immune responses. This review summarises the rate of COVID-19 infection, maternal antibodies responsiveness, placenta antibody transmission, and adverse events after COVID-19 vaccination in pregnancy studied in epidemiological studies evaluating mRNA vaccines. Potential COVID-19 infection in pregnant women can be prevented using mRNA-based vaccinations. Gestation, childbirth, and perinatal mortality were proven unaffected by COVID-19 vaccination. Injection-site discomfort, tiredness, and migraine are the most prevalent side effects, but these are temporary. After the first dosage of vaccinations, fast antibody responses were demonstrated. The adaptive immunity is found to be more significant after booster vaccination, and is linked to improved placental antigen transmission. Two vaccination doses are associated with more robust maternal and fetal antibody levels. Longer delays between the first immunization dosage and birth are linked to greater fetal IgG antibody levels with reduction in antigen transmission proportion. The mRNA vacciness are effective in reducing the severity of COVID-19 infection and these vaccinations are regarded to be safe options for pregnant women and their unborn fetus. Elsevier Ltd 2021-11-23 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34942/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/34942/2/FULLTEXT.pdf Nang, Kham Oo Leik and Fatimah Ahmedy and Rhanye Mac Guad and Dg Marshitah Pg Baharuddin (2021) Covid-19 vaccine and its consequences in pregnancy: Brief review. Annals of Medicine and Surgery, 72. pp. 1-3. ISSN 2049-0801 https://www.sciencedirect.com/science/article/pii/S2049080121010530?via%3Dihub https://doi.org/10.1016/j.amsu.2021.103103 https://doi.org/10.1016/j.amsu.2021.103103 |
| spellingShingle | QR75-99.5 Bacteria RG551-591 Pregnancy Nang, Kham Oo Leik Fatimah Ahmedy Rhanye Mac Guad Dg Marshitah Pg Baharuddin Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title | Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title_full | Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title_fullStr | Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title_full_unstemmed | Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title_short | Covid-19 vaccine and its consequences in pregnancy: Brief review |
| title_sort | covid 19 vaccine and its consequences in pregnancy brief review |
| topic | QR75-99.5 Bacteria RG551-591 Pregnancy |
| url | https://eprints.ums.edu.my/id/eprint/34942/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34942/2/FULLTEXT.pdf |
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