Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms

Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fract...

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Main Authors: Nurul Ain Ismail, Azlinah Matawali, Fadzilah Awang Kanak, Lee, Ping Chin, How, Siew Eng, Poh, Lucky Wah Goh, Jualang Azlan Gansau
Format: Article
Language:English
English
Published: S.C Jurnalul Pentru Medicina Si Viata S.R.L 2022
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/34991/1/Abstract.pdf
https://eprints.ums.edu.my/id/eprint/34991/2/Full%20text.pdf
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author Nurul Ain Ismail
Azlinah Matawali
Fadzilah Awang Kanak
Lee, Ping Chin
How, Siew Eng
Poh, Lucky Wah Goh
Jualang Azlan Gansau
author_facet Nurul Ain Ismail
Azlinah Matawali
Fadzilah Awang Kanak
Lee, Ping Chin
How, Siew Eng
Poh, Lucky Wah Goh
Jualang Azlan Gansau
author_sort Nurul Ain Ismail
collection UMS
description Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah.
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spelling ums.eprints-349912022-12-05T00:04:54Z https://eprints.ums.edu.my/id/eprint/34991/ Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms Nurul Ain Ismail Azlinah Matawali Fadzilah Awang Kanak Lee, Ping Chin How, Siew Eng Poh, Lucky Wah Goh Jualang Azlan Gansau QK1-989 Botany RV1-431 Botanic, Thomsonian, and eclectic medicine Medicinal plants have been widely used in healthcare based on traditional knowledge. We investigated the antimicrobial activities and phytochemical contents of a plant known as Blumea balsamifera (B. balsamifera), which Sabah native people have used for health benefits. Methanolic extracts and fractions of the leaves of B. balsamifera were tested for their phytochemical contents and their antimicrobial activities against four Gram-negative and five Gram-positive strains of bacteria. The extracts of B. balsamifera showed antimicrobial activities against three Gram-positive, and one Gram-negative bacteria, with the zone of inhibition ranging from 7.8 mm±0.41 to 10.5 mm±0.71. Fraction CE.F7 exerted the broadest antimicrobial activity towards four Gram-positive or Gram-negative bacteria. The phytochemical constituents identified in the extracts were alkaloid, flavonoid, steroid, and cardiac glycosides. The plant extract demonstrated antimicrobial activities and contained multiple phytochemical constituents. Further investigations into potential antimicrobial agents containing promising fractions would validate the medicinal properties of B. balsamifera used in Sabah. S.C Jurnalul Pentru Medicina Si Viata S.R.L 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34991/1/Abstract.pdf text en https://eprints.ums.edu.my/id/eprint/34991/2/Full%20text.pdf Nurul Ain Ismail and Azlinah Matawali and Fadzilah Awang Kanak and Lee, Ping Chin and How, Siew Eng and Poh, Lucky Wah Goh and Jualang Azlan Gansau (2022) Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms. Journal of Medicine and Life, 15. pp. 951-954. ISSN 1844-3117 (E-ISSN) , 1844-122x (P-ISSN) https://medandlife.org/wp-content/uploads/JMedLife-15-0951.pdf https://doi.org/10.25122/jml-2021-0296 https://doi.org/10.25122/jml-2021-0296
spellingShingle QK1-989 Botany
RV1-431 Botanic, Thomsonian, and eclectic medicine
Nurul Ain Ismail
Azlinah Matawali
Fadzilah Awang Kanak
Lee, Ping Chin
How, Siew Eng
Poh, Lucky Wah Goh
Jualang Azlan Gansau
Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_full Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_fullStr Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_full_unstemmed Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_short Antimicrobial activities and phytochemical properties of Blumea balsamifera against pathogenic microorganisms
title_sort antimicrobial activities and phytochemical properties of blumea balsamifera against pathogenic microorganisms
topic QK1-989 Botany
RV1-431 Botanic, Thomsonian, and eclectic medicine
url https://eprints.ums.edu.my/id/eprint/34991/1/Abstract.pdf
https://eprints.ums.edu.my/id/eprint/34991/2/Full%20text.pdf
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