COVID-19 Treatment—Current Status, Advances, and Gap
COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption....
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| Format: | Article |
| Language: | English English |
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MDPI
2022
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| Online Access: | https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf |
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| author | Chian Ho Lee, Ping Chin |
| author_facet | Chian Ho Lee, Ping Chin |
| author_sort | Chian Ho |
| collection | UMS |
| description | COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption. While clinical trials on therapeutic drugs are going on in an Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership collaboration, current therapeutic approaches and options to counter COVID-19 remain few. Therapeutic drugs include the FDA-approved antiviral drugs, Remdesivir, and an immune modulator, Baricitinib. Hence, therapeutic approaches and alternatives for COVID-19 treatment need to be broadened. This paper discusses efforts in approaches to find treatment for COVID-19, such as inhibiting viral entry and disrupting the virus life cycle, and highlights the gap that needs to be filled in these approaches. |
| first_indexed | 2024-03-06T03:22:52Z |
| format | Article |
| id | ums.eprints-35232 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:22:52Z |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | dspace |
| spelling | ums.eprints-352322023-03-23T02:12:51Z https://eprints.ums.edu.my/id/eprint/35232/ COVID-19 Treatment—Current Status, Advances, and Gap Chian Ho Lee, Ping Chin RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection COVID-19, which emerged in December 2019, was declared a global pandemic by the World Health Organization (WHO) in March 2020. The disease was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has caused millions of deaths worldwide and caused social and economic disruption. While clinical trials on therapeutic drugs are going on in an Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) public–private partnership collaboration, current therapeutic approaches and options to counter COVID-19 remain few. Therapeutic drugs include the FDA-approved antiviral drugs, Remdesivir, and an immune modulator, Baricitinib. Hence, therapeutic approaches and alternatives for COVID-19 treatment need to be broadened. This paper discusses efforts in approaches to find treatment for COVID-19, such as inhibiting viral entry and disrupting the virus life cycle, and highlights the gap that needs to be filled in these approaches. MDPI 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf text en https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf Chian Ho and Lee, Ping Chin (2022) COVID-19 Treatment—Current Status, Advances, and Gap. Pathogens, 11. pp. 1-15. ISSN 2076-0817 https://www.mdpi.com/2076-0817/11/10/1201 https://doi.org/10.3390/pathogens11101201 https://doi.org/10.3390/pathogens11101201 |
| spellingShingle | RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection Chian Ho Lee, Ping Chin COVID-19 Treatment—Current Status, Advances, and Gap |
| title | COVID-19 Treatment—Current Status, Advances, and Gap |
| title_full | COVID-19 Treatment—Current Status, Advances, and Gap |
| title_fullStr | COVID-19 Treatment—Current Status, Advances, and Gap |
| title_full_unstemmed | COVID-19 Treatment—Current Status, Advances, and Gap |
| title_short | COVID-19 Treatment—Current Status, Advances, and Gap |
| title_sort | covid 19 treatment current status advances and gap |
| topic | RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection |
| url | https://eprints.ums.edu.my/id/eprint/35232/1/Abstract.pdf https://eprints.ums.edu.my/id/eprint/35232/2/Full%20text.pdf |
| work_keys_str_mv | AT chianho covid19treatmentcurrentstatusadvancesandgap AT leepingchin covid19treatmentcurrentstatusadvancesandgap |