Comprehensive study on transglycosylation of CGTase from various sources
Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high regionspecificity, low production cost, and mild processing conditions. One of...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/36469/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/36469/2/FULL%20TEXT.pdf |
| _version_ | 1796911846197821440 |
|---|---|
| author | Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid Babak Rasti Joko Sulistyo Mansoor Abdul Hamid |
| author_facet | Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid Babak Rasti Joko Sulistyo Mansoor Abdul Hamid |
| author_sort | Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid |
| collection | UMS |
| description | Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high regionspecificity, low production cost, and mild processing conditions. One of the enzymes commonly used in the transglycosylation reaction is cyclodextrin glucanotransferase (CGTase). The transglycosylated products, catalyzed by CGTase, are widely used in food additives, supplements, and personal care and cosmetic products. This is due to improvements in the solubility, stability, bioactivity and length of the synthesized products. This paper's focus is on the importance of enzymes used in the transglycosylation reaction, their characteristics and mechanism of action, sources and production yield, and donor and acceptor specificities. Moreover, the influence of intrinsic and extrinsic factors on the enzymatic reaction, catalysis of glycosidic linkages, and advantages of CGTase transglycosylation reactions are discussed in detail. |
| first_indexed | 2024-03-06T03:24:49Z |
| format | Article |
| id | ums.eprints-36469 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:24:49Z |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | ums.eprints-364692023-08-17T05:40:33Z https://eprints.ums.edu.my/id/eprint/36469/ Comprehensive study on transglycosylation of CGTase from various sources Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid Babak Rasti Joko Sulistyo Mansoor Abdul Hamid QP501-801 Animal biochemistry RC31-1245 Internal medicine TP250-261 Industrial electrochemistry Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high regionspecificity, low production cost, and mild processing conditions. One of the enzymes commonly used in the transglycosylation reaction is cyclodextrin glucanotransferase (CGTase). The transglycosylated products, catalyzed by CGTase, are widely used in food additives, supplements, and personal care and cosmetic products. This is due to improvements in the solubility, stability, bioactivity and length of the synthesized products. This paper's focus is on the importance of enzymes used in the transglycosylation reaction, their characteristics and mechanism of action, sources and production yield, and donor and acceptor specificities. Moreover, the influence of intrinsic and extrinsic factors on the enzymatic reaction, catalysis of glycosidic linkages, and advantages of CGTase transglycosylation reactions are discussed in detail. Elsevier 2021-02 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/36469/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/36469/2/FULL%20TEXT.pdf Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid and Babak Rasti and Joko Sulistyo and Mansoor Abdul Hamid (2021) Comprehensive study on transglycosylation of CGTase from various sources. Heliyon, 7. pp. 1-16. ISSN 2405-8440 https://doi.org/10.1016/j.heliyon.2021.e06305 |
| spellingShingle | QP501-801 Animal biochemistry RC31-1245 Internal medicine TP250-261 Industrial electrochemistry Chin Hui Lim, Chin Hui Lim, Babak Rasti, Joko Sulistyo, Mansoor Abdul Hamid Babak Rasti Joko Sulistyo Mansoor Abdul Hamid Comprehensive study on transglycosylation of CGTase from various sources |
| title | Comprehensive study on transglycosylation of CGTase from various sources |
| title_full | Comprehensive study on transglycosylation of CGTase from various sources |
| title_fullStr | Comprehensive study on transglycosylation of CGTase from various sources |
| title_full_unstemmed | Comprehensive study on transglycosylation of CGTase from various sources |
| title_short | Comprehensive study on transglycosylation of CGTase from various sources |
| title_sort | comprehensive study on transglycosylation of cgtase from various sources |
| topic | QP501-801 Animal biochemistry RC31-1245 Internal medicine TP250-261 Industrial electrochemistry |
| url | https://eprints.ums.edu.my/id/eprint/36469/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/36469/2/FULL%20TEXT.pdf |
| work_keys_str_mv | AT chinhuilimchinhuilimbabakrastijokosulistyomansoorabdulhamid comprehensivestudyontransglycosylationofcgtasefromvarioussources AT babakrasti comprehensivestudyontransglycosylationofcgtasefromvarioussources AT jokosulistyo comprehensivestudyontransglycosylationofcgtasefromvarioussources AT mansoorabdulhamid comprehensivestudyontransglycosylationofcgtasefromvarioussources |