The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum
The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-...
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| Format: | Article |
| Language: | English English |
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Penerbit UMS
2022
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| Online Access: | https://eprints.ums.edu.my/id/eprint/37410/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/37410/2/FULL%20TEXT.pdf |
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| author | Kazuki Tani Charles Santhanaraju Vairappan |
| author_facet | Kazuki Tani Charles Santhanaraju Vairappan |
| author_sort | Kazuki Tani |
| collection | UMS |
| description | The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4βhydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals. |
| first_indexed | 2024-03-06T03:25:35Z |
| format | Article |
| id | ums.eprints-37410 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:25:35Z |
| publishDate | 2022 |
| publisher | Penerbit UMS |
| record_format | dspace |
| spelling | ums.eprints-374102023-09-26T02:19:17Z https://eprints.ums.edu.my/id/eprint/37410/ The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum Kazuki Tani Charles Santhanaraju Vairappan QL1-355 General Including geographical distribution SH33-134.6 By region or country The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4βhydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals. Penerbit UMS 2022 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/37410/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/37410/2/FULL%20TEXT.pdf Kazuki Tani and Charles Santhanaraju Vairappan (2022) The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum. Journal of Tropical Biology and Conservation, 19. pp. 67-76. ISSN 1823-3902 https://doi.org/10.51200/jtbc.v19i.3938 |
| spellingShingle | QL1-355 General Including geographical distribution SH33-134.6 By region or country Kazuki Tani Charles Santhanaraju Vairappan The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title | The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title_full | The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title_fullStr | The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title_full_unstemmed | The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title_short | The Chemotaxonomic Identification Using Structure Types of Secondary Metabolites and Their Bioactivities of Bornean Litophyton arboretum |
| title_sort | chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of bornean litophyton arboretum |
| topic | QL1-355 General Including geographical distribution SH33-134.6 By region or country |
| url | https://eprints.ums.edu.my/id/eprint/37410/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/37410/2/FULL%20TEXT.pdf |
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