COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images
COVID-19, an infectious coronavirus disease, has triggered a pandemic that has claimed many lives. Clinical institutes have long considered computed tomography (CT) as an excellent and complementary screening method to reverse transcriptase-polymerase chain reaction (RT-PCR). Because of the limited...
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| Format: | Article |
| Language: | English English |
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Molecular Diversity Preservation International (MDPI)
2023
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| Online Access: | https://eprints.ums.edu.my/id/eprint/37668/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/37668/2/FULL%20TEXT.pdf |
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| author | Maisarah Mohd Sufian Ervin Gubin Moung Mohd Hanafi Ahmad Hijazi Farashazillah Yahya Jamal Ahmad Dargham Ali Farzamnia Florence Sia Fui Sze Nur Faraha Mohd Naim |
| author_facet | Maisarah Mohd Sufian Ervin Gubin Moung Mohd Hanafi Ahmad Hijazi Farashazillah Yahya Jamal Ahmad Dargham Ali Farzamnia Florence Sia Fui Sze Nur Faraha Mohd Naim |
| author_sort | Maisarah Mohd Sufian |
| collection | UMS |
| description | COVID-19, an infectious coronavirus disease, has triggered a pandemic that has claimed many lives. Clinical institutes have long considered computed tomography (CT) as an excellent and complementary screening method to reverse transcriptase-polymerase chain reaction (RT-PCR). Because of the limited dataset available on COVID-19, transfer learning-based models have become the go-to solutions for automatic COVID-19 detection. However, CT images are typically provided in grayscale, thus posing a challenge for automatic detection using pre-trained models, which were previously trained on RGB images. Several methods have been proposed in the literature for converting grayscale images to RGB (three-channel) images for use with pre-trained deep-learning models, such as pseudo-colorization, replication, and colorization. The most common method is replication, where the one-channel grayscale image is repeated in the three-channel image. While this technique is simple, it does not provide new information and can lead to poor performance due to redundant image features fed into the DL model. This study proposes a novel image pre-processing method for grayscale medical images that utilize Histogram Equalization (HE) and Contrast Limited Adaptive Histogram Equalization (CLAHE) to create a three-channel image representation that provides different information on each channel. The effectiveness of this method is evaluated using six other pre-trained models, including InceptionV3, MobileNet, ResNet50, VGG16, ViT-B16, and ViTB32. The results show that the proposed image representation significantly improves the classification performance of the models, with the InceptionV3 model achieving an accuracy of 99.60% and a recall (also referred as sensitivity) of 99.59%. The proposed method addresses the limitation of using grayscale medical images for COVID-19 detection and can potentially improve the early detection and control of the disease. Additionally, the proposed method can be applied to other medical imaging tasks with a grayscale image input, thus making it a generalizable solution. |
| first_indexed | 2024-03-06T03:26:13Z |
| format | Article |
| id | ums.eprints-37668 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:26:13Z |
| publishDate | 2023 |
| publisher | Molecular Diversity Preservation International (MDPI) |
| record_format | dspace |
| spelling | ums.eprints-376682023-11-24T07:08:28Z https://eprints.ums.edu.my/id/eprint/37668/ COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images Maisarah Mohd Sufian Ervin Gubin Moung Mohd Hanafi Ahmad Hijazi Farashazillah Yahya Jamal Ahmad Dargham Ali Farzamnia Florence Sia Fui Sze Nur Faraha Mohd Naim R5-920 Medicine (General) RA421-790.95 Public health. Hygiene. Preventive medicine COVID-19, an infectious coronavirus disease, has triggered a pandemic that has claimed many lives. Clinical institutes have long considered computed tomography (CT) as an excellent and complementary screening method to reverse transcriptase-polymerase chain reaction (RT-PCR). Because of the limited dataset available on COVID-19, transfer learning-based models have become the go-to solutions for automatic COVID-19 detection. However, CT images are typically provided in grayscale, thus posing a challenge for automatic detection using pre-trained models, which were previously trained on RGB images. Several methods have been proposed in the literature for converting grayscale images to RGB (three-channel) images for use with pre-trained deep-learning models, such as pseudo-colorization, replication, and colorization. The most common method is replication, where the one-channel grayscale image is repeated in the three-channel image. While this technique is simple, it does not provide new information and can lead to poor performance due to redundant image features fed into the DL model. This study proposes a novel image pre-processing method for grayscale medical images that utilize Histogram Equalization (HE) and Contrast Limited Adaptive Histogram Equalization (CLAHE) to create a three-channel image representation that provides different information on each channel. The effectiveness of this method is evaluated using six other pre-trained models, including InceptionV3, MobileNet, ResNet50, VGG16, ViT-B16, and ViTB32. The results show that the proposed image representation significantly improves the classification performance of the models, with the InceptionV3 model achieving an accuracy of 99.60% and a recall (also referred as sensitivity) of 99.59%. The proposed method addresses the limitation of using grayscale medical images for COVID-19 detection and can potentially improve the early detection and control of the disease. Additionally, the proposed method can be applied to other medical imaging tasks with a grayscale image input, thus making it a generalizable solution. Molecular Diversity Preservation International (MDPI) 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/37668/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/37668/2/FULL%20TEXT.pdf Maisarah Mohd Sufian and Ervin Gubin Moung and Mohd Hanafi Ahmad Hijazi and Farashazillah Yahya and Jamal Ahmad Dargham and Ali Farzamnia and Florence Sia Fui Sze and Nur Faraha Mohd Naim (2023) COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images. Big Data and Cognitive Computing, 7. pp. 1-25. https://doi.org/10.3390/bdcc7010036 |
| spellingShingle | R5-920 Medicine (General) RA421-790.95 Public health. Hygiene. Preventive medicine Maisarah Mohd Sufian Ervin Gubin Moung Mohd Hanafi Ahmad Hijazi Farashazillah Yahya Jamal Ahmad Dargham Ali Farzamnia Florence Sia Fui Sze Nur Faraha Mohd Naim COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title | COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title_full | COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title_fullStr | COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title_full_unstemmed | COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title_short | COVID-19 Classification through Deep Learning Models with Three-Channel Grayscale CT Images |
| title_sort | covid 19 classification through deep learning models with three channel grayscale ct images |
| topic | R5-920 Medicine (General) RA421-790.95 Public health. Hygiene. Preventive medicine |
| url | https://eprints.ums.edu.my/id/eprint/37668/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/37668/2/FULL%20TEXT.pdf |
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