Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. T...

Full description

Bibliographic Details
Main Authors: Mohd Azrie Awang, Mohammad Amil Zulhilmi Benjamin, Adilah Anuar, Mohd Fakhrulddin Ismail, Shiamala Devi Ramaiya, Siti Nur Aisyah Mohd Hashim
Format: Article
Language:English
English
Published: Elsevier Inc. 2023
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/38134/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38134/2/FULL%20TEXT.pdf
_version_ 1796912030510219264
author Mohd Azrie Awang
Mohammad Amil Zulhilmi Benjamin
Adilah Anuar
Mohd Fakhrulddin Ismail
Shiamala Devi Ramaiya
Siti Nur Aisyah Mohd Hashim
author_facet Mohd Azrie Awang
Mohammad Amil Zulhilmi Benjamin
Adilah Anuar
Mohd Fakhrulddin Ismail
Shiamala Devi Ramaiya
Siti Nur Aisyah Mohd Hashim
author_sort Mohd Azrie Awang
collection UMS
description The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the waterextracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of L. pumila leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of L. pumila leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications.
first_indexed 2024-03-06T03:27:29Z
format Article
id ums.eprints-38134
institution Universiti Malaysia Sabah
language English
English
last_indexed 2024-03-06T03:27:29Z
publishDate 2023
publisher Elsevier Inc.
record_format dspace
spelling ums.eprints-381342024-02-05T07:26:41Z https://eprints.ums.edu.my/id/eprint/38134/ Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves Mohd Azrie Awang Mohammad Amil Zulhilmi Benjamin Adilah Anuar Mohd Fakhrulddin Ismail Shiamala Devi Ramaiya Siti Nur Aisyah Mohd Hashim QH573-671 Cytology TN1-997 Mining engineering. Metallurgy The article presents data on the quantification of gallic acid (GA) and the assessment of the antioxidant and anti-inflammatory properties of Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves using various solvents. GA was quantified using high-performance liquid chromatography analysis. Total phenolic content (TPC) was assessed using the Folin-Ciocalteu method. The antioxidant activities were evaluated using xanthine oxidase superoxide (XOD-Superoxide) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays, while anti-inflammatory activities were examined through lipoxygenase (LOX) and xanthine oxidase (XOD) inhibition assays. Results showed that the waterextracted sample had the highest GA and TPC among the solvents tested, along with the strongest inhibition activities in the XOD-Superoxide and DPPH assays. Both water and ethanol extracts showed significant inhibitory activities in the LOX assay but were inactive in the XOD assay. These findings suggest that the bioactivity of L. pumila leaf extract is associated with GA and TPC. GA and TPC strongly correlated with antioxidant and anti-inflammatory activities, except for the XOD assay. The dataset highlights the potential dietary benefits of L. pumila leaves as a natural source of antioxidants and anti-inflammatory properties for pharmaceutical and nutraceutical applications. Elsevier Inc. 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/38134/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/38134/2/FULL%20TEXT.pdf Mohd Azrie Awang and Mohammad Amil Zulhilmi Benjamin and Adilah Anuar and Mohd Fakhrulddin Ismail and Shiamala Devi Ramaiya and Siti Nur Aisyah Mohd Hashim (2023) Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves. Data in Brief, 51. pp. 1-7. ISSN 2352-3409 https://doi.org/10.1016/j.dib.2023.109644
spellingShingle QH573-671 Cytology
TN1-997 Mining engineering. Metallurgy
Mohd Azrie Awang
Mohammad Amil Zulhilmi Benjamin
Adilah Anuar
Mohd Fakhrulddin Ismail
Shiamala Devi Ramaiya
Siti Nur Aisyah Mohd Hashim
Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_fullStr Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full_unstemmed Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_short Dataset of gallic acid quantification and their antioxidant and anti-inflammatory activities of different solvent extractions from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_sort dataset of gallic acid quantification and their antioxidant and anti inflammatory activities of different solvent extractions from kacip fatimah labisia pumila benth hook f leaves
topic QH573-671 Cytology
TN1-997 Mining engineering. Metallurgy
url https://eprints.ums.edu.my/id/eprint/38134/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38134/2/FULL%20TEXT.pdf
work_keys_str_mv AT mohdazrieawang datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves
AT mohammadamilzulhilmibenjamin datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves
AT adilahanuar datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves
AT mohdfakhrulddinismail datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves
AT shiamaladeviramaiya datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves
AT sitinuraisyahmohdhashim datasetofgallicacidquantificationandtheirantioxidantandantiinflammatoryactivitiesofdifferentsolventextractionsfromkacipfatimahlabisiapumilabenthhookfleaves