Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects
Breast cancer is considered the second-leading cancer after lung cancer and is the most prevalent cancer among women globally. Currently, cancer immunotherapy via vaccine has gained great attention due to specific and targeted immune cell activity that creates a potent immune response, thus providin...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English English |
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Multidisciplinary Digital Publishing Institute
2023
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/38605/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/38605/2/FULL%20TEXT.pdf |
| _version_ | 1825715563203133440 |
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| author | Muhammad Luqman Nordin Ahmad Khusairi Azemi Abu Hassan Nordin Walid Nabgan Pei, Yuen Ng Khatijah Yusoff Nadiah Abu Kue, Peng Lim Zainul Amiruddin Zakaria Noraznawati Ismail Fazren Azmi |
| author_facet | Muhammad Luqman Nordin Ahmad Khusairi Azemi Abu Hassan Nordin Walid Nabgan Pei, Yuen Ng Khatijah Yusoff Nadiah Abu Kue, Peng Lim Zainul Amiruddin Zakaria Noraznawati Ismail Fazren Azmi |
| author_sort | Muhammad Luqman Nordin |
| collection | UMS |
| description | Breast cancer is considered the second-leading cancer after lung cancer and is the most prevalent cancer among women globally. Currently, cancer immunotherapy via vaccine has gained great attention due to specific and targeted immune cell activity that creates a potent immune response, thus providing long-lasting protection against the disease. Despite peptides being very susceptible to enzymatic degradation and poor immunogenicity, they can be easily customized with selected epitopes to induce a specific immune response and particulate with carriers to improve their delivery and thus overcome their weaknesses. With advances in nanotechnology, the peptide-based vaccine could incorporate other components, thereby modulating the immune system response against breast cancer. Considering that peptide-based vaccines seem to show remarkably promising outcomes against cancer, this review focuses on and provides a specific view of peptide-based vaccines used against breast cancer. Here, we discuss the benefits associated with a peptide-based vaccine, which can be a mainstay in the prevention and recurrence of breast cancer. Additionally, we also report the results of recent trials as well as plausible prospects for nanotechnology against breast cancer. |
| first_indexed | 2024-09-24T00:48:49Z |
| format | Article |
| id | ums.eprints-38605 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-09-24T00:48:49Z |
| publishDate | 2023 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | dspace |
| spelling | ums.eprints-386052024-05-02T08:47:34Z https://eprints.ums.edu.my/id/eprint/38605/ Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects Muhammad Luqman Nordin Ahmad Khusairi Azemi Abu Hassan Nordin Walid Nabgan Pei, Yuen Ng Khatijah Yusoff Nadiah Abu Kue, Peng Lim Zainul Amiruddin Zakaria Noraznawati Ismail Fazren Azmi RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RM270-282 Immunotherapy. Serotherapy Breast cancer is considered the second-leading cancer after lung cancer and is the most prevalent cancer among women globally. Currently, cancer immunotherapy via vaccine has gained great attention due to specific and targeted immune cell activity that creates a potent immune response, thus providing long-lasting protection against the disease. Despite peptides being very susceptible to enzymatic degradation and poor immunogenicity, they can be easily customized with selected epitopes to induce a specific immune response and particulate with carriers to improve their delivery and thus overcome their weaknesses. With advances in nanotechnology, the peptide-based vaccine could incorporate other components, thereby modulating the immune system response against breast cancer. Considering that peptide-based vaccines seem to show remarkably promising outcomes against cancer, this review focuses on and provides a specific view of peptide-based vaccines used against breast cancer. Here, we discuss the benefits associated with a peptide-based vaccine, which can be a mainstay in the prevention and recurrence of breast cancer. Additionally, we also report the results of recent trials as well as plausible prospects for nanotechnology against breast cancer. Multidisciplinary Digital Publishing Institute 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/38605/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/38605/2/FULL%20TEXT.pdf Muhammad Luqman Nordin and Ahmad Khusairi Azemi and Abu Hassan Nordin and Walid Nabgan and Pei, Yuen Ng and Khatijah Yusoff and Nadiah Abu and Kue, Peng Lim and Zainul Amiruddin Zakaria and Noraznawati Ismail and Fazren Azmi (2023) Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects. Pharmaceuticals, 16. pp. 1-26. https://doi.org/10.3390/ph16070923 |
| spellingShingle | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RM270-282 Immunotherapy. Serotherapy Muhammad Luqman Nordin Ahmad Khusairi Azemi Abu Hassan Nordin Walid Nabgan Pei, Yuen Ng Khatijah Yusoff Nadiah Abu Kue, Peng Lim Zainul Amiruddin Zakaria Noraznawati Ismail Fazren Azmi Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title | Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title_full | Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title_fullStr | Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title_full_unstemmed | Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title_short | Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects |
| title_sort | peptide based vaccine against breast cancer recent advances and prospects |
| topic | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RM270-282 Immunotherapy. Serotherapy |
| url | https://eprints.ums.edu.my/id/eprint/38605/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/38605/2/FULL%20TEXT.pdf |
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