The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-...
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Language: | English English |
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Universiti Malaysia Sabah
2022
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Online Access: | https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf |
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author | Kazuki Tani Charles S. Vairappan |
author_facet | Kazuki Tani Charles S. Vairappan |
author_sort | Kazuki Tani |
collection | UMS |
description | The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4β-hydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals. |
first_indexed | 2024-09-24T00:49:01Z |
format | Article |
id | ums.eprints-38677 |
institution | Universiti Malaysia Sabah |
language | English English |
last_indexed | 2024-09-24T00:49:01Z |
publishDate | 2022 |
publisher | Universiti Malaysia Sabah |
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spelling | ums.eprints-386772024-05-15T03:29:10Z https://eprints.ums.edu.my/id/eprint/38677/ The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum Kazuki Tani Charles S. Vairappan QK710-899 Plant physiology The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4β-hydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals. Universiti Malaysia Sabah 2022 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf Kazuki Tani and Charles S. Vairappan (2022) The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum. Journal Of Tropical Biology And Conservation, 19. pp. 67-76. ISSN 1823-3902 https://doi.org/10.51200/jtbc.v19i.3938 |
spellingShingle | QK710-899 Plant physiology Kazuki Tani Charles S. Vairappan The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title | The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title_full | The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title_fullStr | The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title_full_unstemmed | The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title_short | The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum |
title_sort | chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of bornean litophyton arboreum |
topic | QK710-899 Plant physiology |
url | https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf |
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