The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum

The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-...

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Main Authors: Kazuki Tani, Charles S. Vairappan
Format: Article
Language:English
English
Published: Universiti Malaysia Sabah 2022
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf
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author Kazuki Tani
Charles S. Vairappan
author_facet Kazuki Tani
Charles S. Vairappan
author_sort Kazuki Tani
collection UMS
description The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4β-hydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals.
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spelling ums.eprints-386772024-05-15T03:29:10Z https://eprints.ums.edu.my/id/eprint/38677/ The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum Kazuki Tani Charles S. Vairappan QK710-899 Plant physiology The structure types and bioactivities of secondary metabolites derived from Litophyton arboreum, distributed in Sepanggar Bay, Sabah, Malaysia, were investigated as additional tools for establishing their species identification. As a result, a total of two secondary metabolites (alismol (1) and 10α-methoxy-4β-hydroxy guaian-6-ene (2)) were isolated from Bornean soft coral L. arboreum. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1 and 2 were determined. In addition, the compound 2 showed highest antifungal activity against Haliphthoros milfordensis. As a result of comparison with previous literature, significant variations were observed in relation to structure types of secondary metabolites and bioactivities. Information from this study gives additional evidence of chemotaxonomic significance and baseline data for effective selection of suitable lead pharmaceuticals. Universiti Malaysia Sabah 2022 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf Kazuki Tani and Charles S. Vairappan (2022) The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum. Journal Of Tropical Biology And Conservation, 19. pp. 67-76. ISSN 1823-3902 https://doi.org/10.51200/jtbc.v19i.3938
spellingShingle QK710-899 Plant physiology
Kazuki Tani
Charles S. Vairappan
The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title_full The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title_fullStr The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title_full_unstemmed The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title_short The chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of Bornean litophyton arboreum
title_sort chemotaxonomic identification using structure types of secondary metabolites and their bioactivities of bornean litophyton arboreum
topic QK710-899 Plant physiology
url https://eprints.ums.edu.my/id/eprint/38677/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38677/2/FULLTEXT.pdf
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