First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia
Spinal tuberculosis, also referred to as Pott’s disease, presents a significant risk of severe paralysis if not promptly detected and treated, owing to complications such as spinal cord compression and deformity. This article presents the genetic analysis of a Mycobacterium tuberculosis STB-T1A stra...
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| Format: | Article |
| Language: | English English |
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Elsevier
2024
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| Online Access: | https://eprints.ums.edu.my/id/eprint/39243/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/39243/2/FULL%20TEXT.pdf |
| _version_ | 1825715671097409536 |
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| author | Kai Ling Chin Eraniyah Jastan Suing Ruhini Andong Choong Hoon Foo Sook Kwan Chan Jaeyres Jani Kamruddin Ahmed Zainal Arifin Mustapha |
| author_facet | Kai Ling Chin Eraniyah Jastan Suing Ruhini Andong Choong Hoon Foo Sook Kwan Chan Jaeyres Jani Kamruddin Ahmed Zainal Arifin Mustapha |
| author_sort | Kai Ling Chin |
| collection | UMS |
| description | Spinal tuberculosis, also referred to as Pott’s disease, presents a significant risk of severe paralysis if not promptly detected and treated, owing to complications such as spinal cord compression and deformity. This article presents the genetic analysis of a Mycobacterium tuberculosis STB-T1A strain, isolated from the spine of a 29-year-old female diagnosed with spinal tuberculosis. Genomic DNA was extracted from pure culture and subjected to sequencing using the Illumina NovaSeq 6000 sequencing system. The genome of the M. tuberculosis STB-T1A strain spans 4,367,616 base pairs with a G+C content of 65.56 % and 4174 protein-coding genes. Comparative genomic analysis, conducted via single nucleotide polymorphism (SNP)-based phylogenetic analysis using the Maximum Likelihood method, revealed that the strain falls within the Indo-Oceanic lineage (Lineage 1). It clusters with the M. tuberculosis 43-16836 strain, which was isolated from the cerebrospinal fluid of a patient with tuberculous meningitis in Thailand. The complete genome sequence has been deposited at the National Center for Biotechnology Information (NCBI) GenBank database with the accession number JBBMVZ000000000. |
| first_indexed | 2024-09-24T00:50:32Z |
| format | Article |
| id | ums.eprints-39243 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-09-24T00:50:32Z |
| publishDate | 2024 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | ums.eprints-392432024-07-19T08:22:35Z https://eprints.ums.edu.my/id/eprint/39243/ First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia Kai Ling Chin Eraniyah Jastan Suing Ruhini Andong Choong Hoon Foo Sook Kwan Chan Jaeyres Jani Kamruddin Ahmed Zainal Arifin Mustapha QR75-99.5 Bacteria RC306-320.5 Tuberculosis Spinal tuberculosis, also referred to as Pott’s disease, presents a significant risk of severe paralysis if not promptly detected and treated, owing to complications such as spinal cord compression and deformity. This article presents the genetic analysis of a Mycobacterium tuberculosis STB-T1A strain, isolated from the spine of a 29-year-old female diagnosed with spinal tuberculosis. Genomic DNA was extracted from pure culture and subjected to sequencing using the Illumina NovaSeq 6000 sequencing system. The genome of the M. tuberculosis STB-T1A strain spans 4,367,616 base pairs with a G+C content of 65.56 % and 4174 protein-coding genes. Comparative genomic analysis, conducted via single nucleotide polymorphism (SNP)-based phylogenetic analysis using the Maximum Likelihood method, revealed that the strain falls within the Indo-Oceanic lineage (Lineage 1). It clusters with the M. tuberculosis 43-16836 strain, which was isolated from the cerebrospinal fluid of a patient with tuberculous meningitis in Thailand. The complete genome sequence has been deposited at the National Center for Biotechnology Information (NCBI) GenBank database with the accession number JBBMVZ000000000. Elsevier 2024 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/39243/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/39243/2/FULL%20TEXT.pdf Kai Ling Chin and Eraniyah Jastan Suing and Ruhini Andong and Choong Hoon Foo and Sook Kwan Chan and Jaeyres Jani and Kamruddin Ahmed and Zainal Arifin Mustapha (2024) First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia. Science direct. pp. 1-7. ISSN 2352-3409 https://doi.org/10.1016/j.dib.2024.110476 |
| spellingShingle | QR75-99.5 Bacteria RC306-320.5 Tuberculosis Kai Ling Chin Eraniyah Jastan Suing Ruhini Andong Choong Hoon Foo Sook Kwan Chan Jaeyres Jani Kamruddin Ahmed Zainal Arifin Mustapha First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title | First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title_full | First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title_fullStr | First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title_full_unstemmed | First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title_short | First whole genome sequencing data of a Mycobacterium tuberculosis STB-T1A strain isolated from a spinal tuberculosis patient in Sabah, Malaysia |
| title_sort | first whole genome sequencing data of a mycobacterium tuberculosis stb t1a strain isolated from a spinal tuberculosis patient in sabah malaysia |
| topic | QR75-99.5 Bacteria RC306-320.5 Tuberculosis |
| url | https://eprints.ums.edu.my/id/eprint/39243/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/39243/2/FULL%20TEXT.pdf |
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