The role of estrogen across multiple disease mechanisms
Estrogen is a significant hormone that is involved in a multitude of physiological and pathological processes. In addition to its pivotal role in the reproductive system, estrogen is also implicated in the pathogenesis of a multitude of diseases. Nevertheless, previous research on the role of estrog...
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| Format: | Article |
| Language: | English English |
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MDPI
2024
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| Online Access: | https://eprints.ums.edu.my/id/eprint/41242/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41242/2/FULL%20TEXT.pdf |
| _version_ | 1825715832835014656 |
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| author | Xiuting Xiang Praneetha Palasuberniam Rahmawati Pare |
| author_facet | Xiuting Xiang Praneetha Palasuberniam Rahmawati Pare |
| author_sort | Xiuting Xiang |
| collection | UMS |
| description | Estrogen is a significant hormone that is involved in a multitude of physiological and pathological processes. In addition to its pivotal role in the reproductive system, estrogen is also implicated in the pathogenesis of a multitude of diseases. Nevertheless, previous research on the role of estrogen in a multitude of diseases, including Alzheimer’s disease, depression, cardiovascular disease, diabetes, osteoporosis, gastrointestinal diseases, and estrogen-dependent cancers, has concentrated on a single disease area, resulting in a lack of comprehensive understanding of cross-disease mechanisms. This has brought some challenges to the current treatment methods for these diseases, because estrogen as a potential therapeutic tool has not yet fully developed its potential. Therefore, this review aims to comprehensively explore the mechanism of estrogen in these seven types of diseases. The objective of this study is to describe the relationship between each disease and estrogen, including the ways in which estrogen participates in regulating disease mechanisms, and to outline the efficacy of estrogen in treating these diseases in clinical practice. By studying the role of estrogen in a variety of disease mechanisms, it is hoped that a more accurate theoretical basis and clinical guidance for future treatment strategies will be provided, thus promoting the effective management and treatment of these diseases. |
| first_indexed | 2024-12-09T00:51:59Z |
| format | Article |
| id | ums.eprints-41242 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-12-09T00:51:59Z |
| publishDate | 2024 |
| publisher | MDPI |
| record_format | dspace |
| spelling | ums.eprints-412422024-10-14T01:59:56Z https://eprints.ums.edu.my/id/eprint/41242/ The role of estrogen across multiple disease mechanisms Xiuting Xiang Praneetha Palasuberniam Rahmawati Pare QP501-801 Animal biochemistry RC512-528 Psychoses Estrogen is a significant hormone that is involved in a multitude of physiological and pathological processes. In addition to its pivotal role in the reproductive system, estrogen is also implicated in the pathogenesis of a multitude of diseases. Nevertheless, previous research on the role of estrogen in a multitude of diseases, including Alzheimer’s disease, depression, cardiovascular disease, diabetes, osteoporosis, gastrointestinal diseases, and estrogen-dependent cancers, has concentrated on a single disease area, resulting in a lack of comprehensive understanding of cross-disease mechanisms. This has brought some challenges to the current treatment methods for these diseases, because estrogen as a potential therapeutic tool has not yet fully developed its potential. Therefore, this review aims to comprehensively explore the mechanism of estrogen in these seven types of diseases. The objective of this study is to describe the relationship between each disease and estrogen, including the ways in which estrogen participates in regulating disease mechanisms, and to outline the efficacy of estrogen in treating these diseases in clinical practice. By studying the role of estrogen in a variety of disease mechanisms, it is hoped that a more accurate theoretical basis and clinical guidance for future treatment strategies will be provided, thus promoting the effective management and treatment of these diseases. MDPI 2024 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/41242/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/41242/2/FULL%20TEXT.pdf Xiuting Xiang and Praneetha Palasuberniam and Rahmawati Pare (2024) The role of estrogen across multiple disease mechanisms. Current Issues in Molecular Biology, 46 (8). pp. 1-27. https://doi.org/10.3390/cimb46080483 |
| spellingShingle | QP501-801 Animal biochemistry RC512-528 Psychoses Xiuting Xiang Praneetha Palasuberniam Rahmawati Pare The role of estrogen across multiple disease mechanisms |
| title | The role of estrogen across multiple disease mechanisms |
| title_full | The role of estrogen across multiple disease mechanisms |
| title_fullStr | The role of estrogen across multiple disease mechanisms |
| title_full_unstemmed | The role of estrogen across multiple disease mechanisms |
| title_short | The role of estrogen across multiple disease mechanisms |
| title_sort | role of estrogen across multiple disease mechanisms |
| topic | QP501-801 Animal biochemistry RC512-528 Psychoses |
| url | https://eprints.ums.edu.my/id/eprint/41242/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41242/2/FULL%20TEXT.pdf |
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