The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a revolutionary tool for the diagnosis and staging of mediastinal disorders. Nevertheless, its diagnostic capability is reduced in certain disorders such as lymphoproliferative diseases. EBUS-guided transbronchial medias...
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| Format: | Article |
| Language: | English English |
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Wiley-Blackwell Publishing Ltd
2024
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| Online Access: | https://eprints.ums.edu.my/id/eprint/41861/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41861/2/FULL%20TEXT.pdf |
| _version_ | 1825715937000554496 |
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| author | Nai-Chien Huan Wei Lun Lee Hema Yamini Ramarmuty Larry Ellee Nyanti Melody Shu Ling Tsen Dahziela Yunus |
| author_facet | Nai-Chien Huan Wei Lun Lee Hema Yamini Ramarmuty Larry Ellee Nyanti Melody Shu Ling Tsen Dahziela Yunus |
| author_sort | Nai-Chien Huan |
| collection | UMS |
| description | Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a revolutionary tool for the diagnosis and staging of mediastinal disorders. Nevertheless, its diagnostic capability is reduced in certain disorders such as lymphoproliferative diseases. EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) is a novel technique that can provide larger samples with preserved tissue architecture, with an acceptable safety profile. In this case report, we present a middle-aged gentleman with a huge anterior mediastinal mass and bilateral mediastinal and hilar lymphadenopathy. He underwent EBUS-TBNA with rapid on-site evaluation (ROSE) followed by EBUS-TBMC, all under general anaesthesia. Histopathological analysis showed discordance between EBUS-TBNA and EBUS-TBMC in which only TBMC samples provided adequate tissue to attain a diagnosis of primary mediastinal large B-cell lymphoma. This case report reinforced the diagnostic role of EBUS-TBMC in the diagnosis of lymphoproliferative diseases. |
| first_indexed | 2024-12-09T00:53:48Z |
| format | Article |
| id | ums.eprints-41861 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-12-09T00:53:48Z |
| publishDate | 2024 |
| publisher | Wiley-Blackwell Publishing Ltd |
| record_format | dspace |
| spelling | ums.eprints-418612024-11-12T01:50:28Z https://eprints.ums.edu.my/id/eprint/41861/ The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma Nai-Chien Huan Wei Lun Lee Hema Yamini Ramarmuty Larry Ellee Nyanti Melody Shu Ling Tsen Dahziela Yunus RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RC31-1245 Internal medicine Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a revolutionary tool for the diagnosis and staging of mediastinal disorders. Nevertheless, its diagnostic capability is reduced in certain disorders such as lymphoproliferative diseases. EBUS-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) is a novel technique that can provide larger samples with preserved tissue architecture, with an acceptable safety profile. In this case report, we present a middle-aged gentleman with a huge anterior mediastinal mass and bilateral mediastinal and hilar lymphadenopathy. He underwent EBUS-TBNA with rapid on-site evaluation (ROSE) followed by EBUS-TBMC, all under general anaesthesia. Histopathological analysis showed discordance between EBUS-TBNA and EBUS-TBMC in which only TBMC samples provided adequate tissue to attain a diagnosis of primary mediastinal large B-cell lymphoma. This case report reinforced the diagnostic role of EBUS-TBMC in the diagnosis of lymphoproliferative diseases. Wiley-Blackwell Publishing Ltd 2024 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/41861/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/41861/2/FULL%20TEXT.pdf Nai-Chien Huan and Wei Lun Lee and Hema Yamini Ramarmuty and Larry Ellee Nyanti and Melody Shu Ling Tsen and Dahziela Yunus (2024) The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma. Respirology Case Reports. pp. 1-5. ISSN 2051-3380 https://doi.org/10.1002/rcr2.1342 |
| spellingShingle | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RC31-1245 Internal medicine Nai-Chien Huan Wei Lun Lee Hema Yamini Ramarmuty Larry Ellee Nyanti Melody Shu Ling Tsen Dahziela Yunus The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title | The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title_full | The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title_fullStr | The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title_full_unstemmed | The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title_short | The utility of endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) for the diagnosis of mediastinal lymphoma |
| title_sort | utility of endobronchial ultrasound guided transbronchial mediastinal cryobiopsy ebus tbmc for the diagnosis of mediastinal lymphoma |
| topic | RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RC31-1245 Internal medicine |
| url | https://eprints.ums.edu.my/id/eprint/41861/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41861/2/FULL%20TEXT.pdf |
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