Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl
Numerous studies have provided evidence supporting the significant role of oxidative stress in the development and progression of various diseases. The significance of the capacity of antioxidant status to recuperate from specific diseases has been demonstrated to be crucial for enhancing human heal...
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| Format: | Article |
| Language: | English English |
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Borneo International Journal of Biotechnology (BIJB)
2023
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| Online Access: | https://eprints.ums.edu.my/id/eprint/41917/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41917/2/FULL%20TEXT.pdf |
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| author | Senty Vun-Sang Caysandra Audrey Michelle Elwon Mohammad Iqbal |
| author_facet | Senty Vun-Sang Caysandra Audrey Michelle Elwon Mohammad Iqbal |
| author_sort | Senty Vun-Sang |
| collection | UMS |
| description | Numerous studies have provided evidence supporting the significant role of oxidative stress in the development and progression of various diseases. The significance of the capacity of antioxidant status to recuperate from specific diseases has been demonstrated to be crucial for enhancing human health. Donax grandis, a plant species belonging to the Marantaceae family, is used by the indigenous population of Sabah to treat a range of ailments. This study aimed to chemically analyse the aqueous extract of D. grandis for the presence of bioactive compounds. The analysis revealed the detection of tannins, saponins, and flavonoids within the extract. Quantification of phenolics and flavonoids was conducted to determine their overall content. In-vitro antioxidant activity was investigated using a 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method, employing a UV-VIS spectrophotometer. The phenolic compound concentration was 34.34 ± 1.37 mg/g gallic acid equivalent, while the flavonoid content was 3.93 ± 0.12 mg/g catechin equivalent. The IC50 value of D. grandis in the DPPH assay was determined to be 303.68 ± 0.4 μg/ml. The findings have revealed significant phytochemical properties found in D. grandis, which are anticipated to have therapeutic potential in managing diseases associated with oxidative stress. |
| first_indexed | 2024-12-09T00:53:55Z |
| format | Article |
| id | ums.eprints-41917 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-12-09T00:53:55Z |
| publishDate | 2023 |
| publisher | Borneo International Journal of Biotechnology (BIJB) |
| record_format | dspace |
| spelling | ums.eprints-419172024-11-16T07:29:00Z https://eprints.ums.edu.my/id/eprint/41917/ Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl Senty Vun-Sang Caysandra Audrey Michelle Elwon Mohammad Iqbal QK710-899 Plant physiology RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Numerous studies have provided evidence supporting the significant role of oxidative stress in the development and progression of various diseases. The significance of the capacity of antioxidant status to recuperate from specific diseases has been demonstrated to be crucial for enhancing human health. Donax grandis, a plant species belonging to the Marantaceae family, is used by the indigenous population of Sabah to treat a range of ailments. This study aimed to chemically analyse the aqueous extract of D. grandis for the presence of bioactive compounds. The analysis revealed the detection of tannins, saponins, and flavonoids within the extract. Quantification of phenolics and flavonoids was conducted to determine their overall content. In-vitro antioxidant activity was investigated using a 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging method, employing a UV-VIS spectrophotometer. The phenolic compound concentration was 34.34 ± 1.37 mg/g gallic acid equivalent, while the flavonoid content was 3.93 ± 0.12 mg/g catechin equivalent. The IC50 value of D. grandis in the DPPH assay was determined to be 303.68 ± 0.4 μg/ml. The findings have revealed significant phytochemical properties found in D. grandis, which are anticipated to have therapeutic potential in managing diseases associated with oxidative stress. Borneo International Journal of Biotechnology (BIJB) 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/41917/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/41917/2/FULL%20TEXT.pdf Senty Vun-Sang and Caysandra Audrey Michelle Elwon and Mohammad Iqbal (2023) Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl. Borneo International Journal of Biotechnology (BIJB), 3. pp. 1-17. ISSN 2716-697X https://doi.org/10.51200/bijb.v3i.4060 |
| spellingShingle | QK710-899 Plant physiology RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Senty Vun-Sang Caysandra Audrey Michelle Elwon Mohammad Iqbal Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title | Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title_full | Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title_fullStr | Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title_full_unstemmed | Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title_short | Total phenolic, flavonoid content, antioxidant activity and Phytochemical screening of Donax grandis (miq.)ridl |
| title_sort | total phenolic flavonoid content antioxidant activity and phytochemical screening of donax grandis miq ridl |
| topic | QK710-899 Plant physiology RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) |
| url | https://eprints.ums.edu.my/id/eprint/41917/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/41917/2/FULL%20TEXT.pdf |
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