Amphotericin B resistance in Leishmania mexicana: alterations to sterol metabolism and oxidative stress response

Amphotericin B resistance in Leishmania mexicana: alterations to sterol metabolism and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed that, in each resistant...

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Bibliographic Details
Main Authors:	Alpizar-Sosa, Edubiel A., Ithnin, Nur Raihana, Wenbin, Wei, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J. S., Denny, Paul W., Barrett, Michael P.
Format:	Article
Published:	Public Library of Science 2022

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