Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies
Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a r...
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| Format: | Article |
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MDPI
2022
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| author | Molujin, Arnold Marshall Abbasiliasi, Sahar Nurdin, Armania Lee, Ping-Chin Gansau, Jualang Azlan Jawan, Roslina |
| author_facet | Molujin, Arnold Marshall Abbasiliasi, Sahar Nurdin, Armania Lee, Ping-Chin Gansau, Jualang Azlan Jawan, Roslina |
| author_sort | Molujin, Arnold Marshall |
| collection | UPM |
| description | Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines. |
| first_indexed | 2024-03-06T11:13:02Z |
| format | Article |
| id | upm.eprints-100506 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:13:02Z |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | dspace |
| spelling | upm.eprints-1005062023-11-29T06:41:34Z http://psasir.upm.edu.my/id/eprint/100506/ Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies Molujin, Arnold Marshall Abbasiliasi, Sahar Nurdin, Armania Lee, Ping-Chin Gansau, Jualang Azlan Jawan, Roslina Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines. MDPI 2022-09-29 Article PeerReviewed Molujin, Arnold Marshall and Abbasiliasi, Sahar and Nurdin, Armania and Lee, Ping-Chin and Gansau, Jualang Azlan and Jawan, Roslina (2022) Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies. Cancers, 14 (19). art. no. 4758. pp. 1-14. ISSN 2072-6694 https://www.mdpi.com/2072-6694/14/19/4758 10.3390/cancers14194758 |
| spellingShingle | Molujin, Arnold Marshall Abbasiliasi, Sahar Nurdin, Armania Lee, Ping-Chin Gansau, Jualang Azlan Jawan, Roslina Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title | Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title_full | Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title_fullStr | Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title_full_unstemmed | Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title_short | Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies |
| title_sort | bacteriocins as potential therapeutic approaches in the treatment of various cancers a review of in vitro studies |
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