Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient
We report a clinical and laboratory observation in a boy with X-linked agammaglobulinemia (XLA) who underwent an immunoglobulin replacement therapy (IRT) via the subcutaneous route (IGSC) seven years after his IRT via intravenous route (IGIV). He was free of invasive infections when on IGIV but not...
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| Format: | Article |
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Malaysian Medical Association
2022
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| _version_ | 1796983945459400704 |
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| author | Ali, Adli Abdul Wahab, Asrul Abdul Latiff, Amir Hamzah Ismail, Intan Hakimah Mohd Zaki, Faizah Borhanuddin, Boekhren Karyostyko Mohd Noh, Lokman |
| author_facet | Ali, Adli Abdul Wahab, Asrul Abdul Latiff, Amir Hamzah Ismail, Intan Hakimah Mohd Zaki, Faizah Borhanuddin, Boekhren Karyostyko Mohd Noh, Lokman |
| author_sort | Ali, Adli |
| collection | UPM |
| description | We report a clinical and laboratory observation in a boy with X-linked agammaglobulinemia (XLA) who underwent an immunoglobulin replacement therapy (IRT) via the subcutaneous route (IGSC) seven years after his IRT via intravenous route (IGIV). He was free of invasive infections when on IGIV but not the troublesome coughs a week before the next infusion. A switch to a subcutaneous route resulted in significant improvement of symptoms with good weight gain. When on 2-weekly IGSC cycle, adjusting dose for weight resulted in an IgG trough level of > 600 mg/dl. |
| first_indexed | 2024-03-06T11:13:36Z |
| format | Article |
| id | upm.eprints-100706 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:13:36Z |
| publishDate | 2022 |
| publisher | Malaysian Medical Association |
| record_format | dspace |
| spelling | upm.eprints-1007062023-09-15T07:56:45Z http://psasir.upm.edu.my/id/eprint/100706/ Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient Ali, Adli Abdul Wahab, Asrul Abdul Latiff, Amir Hamzah Ismail, Intan Hakimah Mohd Zaki, Faizah Borhanuddin, Boekhren Karyostyko Mohd Noh, Lokman We report a clinical and laboratory observation in a boy with X-linked agammaglobulinemia (XLA) who underwent an immunoglobulin replacement therapy (IRT) via the subcutaneous route (IGSC) seven years after his IRT via intravenous route (IGIV). He was free of invasive infections when on IGIV but not the troublesome coughs a week before the next infusion. A switch to a subcutaneous route resulted in significant improvement of symptoms with good weight gain. When on 2-weekly IGSC cycle, adjusting dose for weight resulted in an IgG trough level of > 600 mg/dl. Malaysian Medical Association 2022-01 Article PeerReviewed Ali, Adli and Abdul Wahab, Asrul and Abdul Latiff, Amir Hamzah and Ismail, Intan Hakimah and Mohd Zaki, Faizah and Borhanuddin, Boekhren Karyostyko and Mohd Noh, Lokman (2022) Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient. Medical Journal of Malaysia, 77 (1). 95 - 97. ISSN 0300-5283 https://www.e-mjm.org/2022/v77n1/index.html |
| spellingShingle | Ali, Adli Abdul Wahab, Asrul Abdul Latiff, Amir Hamzah Ismail, Intan Hakimah Mohd Zaki, Faizah Borhanuddin, Boekhren Karyostyko Mohd Noh, Lokman Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title | Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title_full | Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title_fullStr | Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title_full_unstemmed | Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title_short | Clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a Malaysian X-linked agammaglobulinemia patient |
| title_sort | clinical and laboratory observation on immunoglobulin replacement therapy switching from an intravenous to a subcutaneous route in a malaysian x linked agammaglobulinemia patient |
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