Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors
Continuous epoxidation of terpenes with H2O2 was carried out using mesoscale oscillatory baffled reactors (meso-OBRs) in a solvent-free environment. The performance of the new 3D-printed single, tri- and multi-orifice baffles was compared with helical and integral baffles. The performance investigat...
| Autori principali: | , , , , |
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| Natura: | Articolo |
| Pubblicazione: |
Elsevier
2022
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| _version_ | 1825938437890375680 |
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| author | Gunam Resul, Mohamad Faiz Mukhtar Abdul Rehman Fern´andez, Ana María L´opez Eze, Valentine C. Harvey, Adam P. |
| author_facet | Gunam Resul, Mohamad Faiz Mukhtar Abdul Rehman Fern´andez, Ana María L´opez Eze, Valentine C. Harvey, Adam P. |
| author_sort | Gunam Resul, Mohamad Faiz Mukhtar |
| collection | UPM |
| description | Continuous epoxidation of terpenes with H2O2 was carried out using mesoscale oscillatory baffled reactors (meso-OBRs) in a solvent-free environment. The performance of the new 3D-printed single, tri- and multi-orifice baffles was compared with helical and integral baffles. The performance investigated includes mixing intensity, induction period, steady-state attainment, and heat removal capability of the meso-OBR. Moreover, passive isothermalisation was also investigated using meso-OBR in a heat pipe assembly. The tri- and multi-orifice baffles were able to overcome mixing limitations and achieved a comparable rate of reaction to batch at mixing conditions of Reo > 850 and Reo > 500, respectively. Both baffles exhibited rapid steady-state attainment, shorter induction period (t = 1.5τ) and better reproducibility with product variation of ∼1.3%. The meso-OBR designs demonstrated effective heat transfer capability, allowing the reaction to being operated isothermally with ±1 °C temperature variation in solvent-free conditions. This removes the need for a solvent, thus reducing reaction volume by a 5-fold. The timescale for the reaction was reduced from ∼8 h in a conventional process to 30 min in the multi-orifice meso-OBR, a 16-fold reduction. A better process has been developed for a continuous epoxidation of terpenes with H2O2 using multi-orifice meso-OBRs, with a potential intensification factor of ∼80. |
| first_indexed | 2024-03-06T11:13:52Z |
| format | Article |
| id | upm.eprints-100803 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:13:52Z |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | upm.eprints-1008032023-08-23T03:28:19Z http://psasir.upm.edu.my/id/eprint/100803/ Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors Gunam Resul, Mohamad Faiz Mukhtar Abdul Rehman Fern´andez, Ana María L´opez Eze, Valentine C. Harvey, Adam P. Continuous epoxidation of terpenes with H2O2 was carried out using mesoscale oscillatory baffled reactors (meso-OBRs) in a solvent-free environment. The performance of the new 3D-printed single, tri- and multi-orifice baffles was compared with helical and integral baffles. The performance investigated includes mixing intensity, induction period, steady-state attainment, and heat removal capability of the meso-OBR. Moreover, passive isothermalisation was also investigated using meso-OBR in a heat pipe assembly. The tri- and multi-orifice baffles were able to overcome mixing limitations and achieved a comparable rate of reaction to batch at mixing conditions of Reo > 850 and Reo > 500, respectively. Both baffles exhibited rapid steady-state attainment, shorter induction period (t = 1.5τ) and better reproducibility with product variation of ∼1.3%. The meso-OBR designs demonstrated effective heat transfer capability, allowing the reaction to being operated isothermally with ±1 °C temperature variation in solvent-free conditions. This removes the need for a solvent, thus reducing reaction volume by a 5-fold. The timescale for the reaction was reduced from ∼8 h in a conventional process to 30 min in the multi-orifice meso-OBR, a 16-fold reduction. A better process has been developed for a continuous epoxidation of terpenes with H2O2 using multi-orifice meso-OBRs, with a potential intensification factor of ∼80. Elsevier 2022-07 Article PeerReviewed Gunam Resul, Mohamad Faiz Mukhtar and Abdul Rehman and Fern´andez, Ana María L´opez and Eze, Valentine C. and Harvey, Adam P. (2022) Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors. Chemical Engineering and Processing - Process Intensification, 177. art. no. 108998. pp. 1-11. ISSN 0255-2701; ESSN: 1873-3204 https://www.sciencedirect.com/science/article/pii/S0255270122002100?via%3Dihub 10.1016/j.cep.2022.108998 |
| spellingShingle | Gunam Resul, Mohamad Faiz Mukhtar Abdul Rehman Fern´andez, Ana María L´opez Eze, Valentine C. Harvey, Adam P. Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title | Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title_full | Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title_fullStr | Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title_full_unstemmed | Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title_short | Continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
| title_sort | continuous process for the epoxidation of terpenes using mesoscale oscillatory baffled reactors |
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