E. tapos yoghurt-a view from nutritional composition and toxicological evaluation
Elateriospermum tapos (E. tapos) is a natural tropical plant that possess a wide range of health benefits. Recent discovery proves that E. tapos extract is able to reduce weight, increase cognitive performance, and ameliorate anxiety and stress hormone. However, this extraction has not been incorpor...
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| Format: | Article |
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Multidisciplinary Digital Publishing Institute
2022
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| _version_ | 1825938520890408960 |
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| author | Naomi, Ruth Mahmad Rusli, Rusydatul Nabila Balan, Santhra Segaran Othman, Fezah Jasni, Azmiza Syawani Jumidil, Siti Hadizah Bahari, Hasnah Yazid, Muhammad Dain |
| author_facet | Naomi, Ruth Mahmad Rusli, Rusydatul Nabila Balan, Santhra Segaran Othman, Fezah Jasni, Azmiza Syawani Jumidil, Siti Hadizah Bahari, Hasnah Yazid, Muhammad Dain |
| author_sort | Naomi, Ruth |
| collection | UPM |
| description | Elateriospermum tapos (E. tapos) is a natural tropical plant that possess a wide range of health benefits. Recent discovery proves that E. tapos extract is able to reduce weight, increase cognitive performance, and ameliorate anxiety and stress hormone. However, this extraction has not been incorporated into yoghurt, and no toxicity studies have been done previously to prove its safety. Thus, this study was aimed to formulate the ethanolic extracted E. tapos into yoghurt and access the toxicological effects on rodents. Forty female Sprague Dawley (SD) rats were used in this study and force fed with either one of the following doses of 250, 500, 1000, or 2000 mg/kg, while the control group received normal saline. The nutritional analysis result showed that the newly formulated yoghurt comprised 328 kJ of energy per 100 mL of servings, 3.6 g of fats, 8.2 g of carbohydrates, 2.7 g of total protein, and 1.2 g of fibre. The peak intensity of Lactobacillus species was observed at 1.6 × 105 CFU/g with a titratable acidity as lactic acid of 0.432 CFU/g, indicating the ability of the formulated yoghurt in stimulating the growth of Lactobacilli. In the experimental study, the E. tapos yoghurt in a single dose (2000 mg/kg) did not show any treatment related to toxicity in any of the rats observed in an additional 14 days. There were no changes in body weight, food and water intake, plasma biochemistry (ALT, AST, ALP, and creatinine), haematological products, and organ weights of the treated groups compared to the subacute control groups. Histological examination of all organs including liver, heart, and kidney were comparable to the control groups. In toto, oral consumptions of E. tapos yoghurt did not induce any adverse effects on rodents. |
| first_indexed | 2024-03-06T11:15:03Z |
| format | Article |
| id | upm.eprints-101308 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:15:03Z |
| publishDate | 2022 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | dspace |
| spelling | upm.eprints-1013082023-10-06T23:23:50Z http://psasir.upm.edu.my/id/eprint/101308/ E. tapos yoghurt-a view from nutritional composition and toxicological evaluation Naomi, Ruth Mahmad Rusli, Rusydatul Nabila Balan, Santhra Segaran Othman, Fezah Jasni, Azmiza Syawani Jumidil, Siti Hadizah Bahari, Hasnah Yazid, Muhammad Dain Elateriospermum tapos (E. tapos) is a natural tropical plant that possess a wide range of health benefits. Recent discovery proves that E. tapos extract is able to reduce weight, increase cognitive performance, and ameliorate anxiety and stress hormone. However, this extraction has not been incorporated into yoghurt, and no toxicity studies have been done previously to prove its safety. Thus, this study was aimed to formulate the ethanolic extracted E. tapos into yoghurt and access the toxicological effects on rodents. Forty female Sprague Dawley (SD) rats were used in this study and force fed with either one of the following doses of 250, 500, 1000, or 2000 mg/kg, while the control group received normal saline. The nutritional analysis result showed that the newly formulated yoghurt comprised 328 kJ of energy per 100 mL of servings, 3.6 g of fats, 8.2 g of carbohydrates, 2.7 g of total protein, and 1.2 g of fibre. The peak intensity of Lactobacillus species was observed at 1.6 × 105 CFU/g with a titratable acidity as lactic acid of 0.432 CFU/g, indicating the ability of the formulated yoghurt in stimulating the growth of Lactobacilli. In the experimental study, the E. tapos yoghurt in a single dose (2000 mg/kg) did not show any treatment related to toxicity in any of the rats observed in an additional 14 days. There were no changes in body weight, food and water intake, plasma biochemistry (ALT, AST, ALP, and creatinine), haematological products, and organ weights of the treated groups compared to the subacute control groups. Histological examination of all organs including liver, heart, and kidney were comparable to the control groups. In toto, oral consumptions of E. tapos yoghurt did not induce any adverse effects on rodents. Multidisciplinary Digital Publishing Institute 2022-06-27 Article PeerReviewed Naomi, Ruth and Mahmad Rusli, Rusydatul Nabila and Balan, Santhra Segaran and Othman, Fezah and Jasni, Azmiza Syawani and Jumidil, Siti Hadizah and Bahari, Hasnah and Yazid, Muhammad Dain (2022) E. tapos yoghurt-a view from nutritional composition and toxicological evaluation. Foods, 11 (13). art. no. 1903. pp. 1-19. ISSN 2304-8158 https://www.mdpi.com/2304-8158/11/13/1903 10.3390/foods11131903 |
| spellingShingle | Naomi, Ruth Mahmad Rusli, Rusydatul Nabila Balan, Santhra Segaran Othman, Fezah Jasni, Azmiza Syawani Jumidil, Siti Hadizah Bahari, Hasnah Yazid, Muhammad Dain E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title | E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title_full | E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title_fullStr | E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title_full_unstemmed | E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title_short | E. tapos yoghurt-a view from nutritional composition and toxicological evaluation |
| title_sort | e tapos yoghurt a view from nutritional composition and toxicological evaluation |
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