Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review

Curcuma caesia or commonly known as black turmeric is belongs to family Zingiberaceae. The rhizome which is the most important part of this species is widely used as a folk medicine for the treatment of asthma, fever, cancer, wounds, allergies, toothache, leprosy, bronchitis, epilepsy, hemorrhoids,...

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Main Authors: Zainol, Haida, Jaafar, Juju Nakasha, Sinniah, Uma Rani, Hakiman, Mansor
Format: Article
Published: Springer 2022
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author Zainol, Haida
Jaafar, Juju Nakasha
Sinniah, Uma Rani
Hakiman, Mansor
author_facet Zainol, Haida
Jaafar, Juju Nakasha
Sinniah, Uma Rani
Hakiman, Mansor
author_sort Zainol, Haida
collection UPM
description Curcuma caesia or commonly known as black turmeric is belongs to family Zingiberaceae. The rhizome which is the most important part of this species is widely used as a folk medicine for the treatment of asthma, fever, cancer, wounds, allergies, toothache, leprosy, bronchitis, epilepsy, hemorrhoids, leukoderma and rheumatoid arthritis. C. caesia is one of the important species of Curcuma which possess various bioactive compounds that responsible for numerous pharmacological activities. The rhizome which is the most prominent feature of the plant is rich with essential oil. In addition, the leaves of this species also consist of essential oil with various bioactive compounds. This review article is aimed to discuss in-depth on botany, ethnomedicinal uses, geographical distribution, propagation, phytochemical studies, pharmacological activities and toxicity of C. caesia. The phytochemical studies revealed that a total of 17 functional groups were detected from rhizome extract of C. caesia. The pharmacological studies conducted demonstrated that C. caesia extract exhibited anti-acne, analgesic, anthelmintic, anti-asthmatic, anti-inflammatory, anti-bacterial, anti-fungal, anti-diabetic, antiproliferative, anticancer, antiulcer, hepatotoxicity, nephrotoxicity, neurotoxicity and cytotoxicity effects. Furthermore, toxicity studies revealed that C. caesia extract is safe for consumption and does not cause toxicity.
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spelling upm.eprints-1013102023-09-22T23:45:59Z http://psasir.upm.edu.my/id/eprint/101310/ Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review Zainol, Haida Jaafar, Juju Nakasha Sinniah, Uma Rani Hakiman, Mansor Curcuma caesia or commonly known as black turmeric is belongs to family Zingiberaceae. The rhizome which is the most important part of this species is widely used as a folk medicine for the treatment of asthma, fever, cancer, wounds, allergies, toothache, leprosy, bronchitis, epilepsy, hemorrhoids, leukoderma and rheumatoid arthritis. C. caesia is one of the important species of Curcuma which possess various bioactive compounds that responsible for numerous pharmacological activities. The rhizome which is the most prominent feature of the plant is rich with essential oil. In addition, the leaves of this species also consist of essential oil with various bioactive compounds. This review article is aimed to discuss in-depth on botany, ethnomedicinal uses, geographical distribution, propagation, phytochemical studies, pharmacological activities and toxicity of C. caesia. The phytochemical studies revealed that a total of 17 functional groups were detected from rhizome extract of C. caesia. The pharmacological studies conducted demonstrated that C. caesia extract exhibited anti-acne, analgesic, anthelmintic, anti-asthmatic, anti-inflammatory, anti-bacterial, anti-fungal, anti-diabetic, antiproliferative, anticancer, antiulcer, hepatotoxicity, nephrotoxicity, neurotoxicity and cytotoxicity effects. Furthermore, toxicity studies revealed that C. caesia extract is safe for consumption and does not cause toxicity. Springer 2022-08-13 Article PeerReviewed Zainol, Haida and Jaafar, Juju Nakasha and Sinniah, Uma Rani and Hakiman, Mansor (2022) Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review. Advances in Traditional Medicine. pp. 1-17. ISSN 2662-4052; ESSN: 2662-4060 https://link.springer.com/article/10.1007/s13596-022-00658-y 10.1007/s13596-022-00658-y
spellingShingle Zainol, Haida
Jaafar, Juju Nakasha
Sinniah, Uma Rani
Hakiman, Mansor
Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title_full Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title_fullStr Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title_full_unstemmed Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title_short Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review
title_sort ethnomedicinal uses phytochemistry pharmacological properties and toxicology of curcuma caesia roxb a review
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