Neuroprotective potentials of honey for cerebral small vessel disease

The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the...

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Main Authors: Che Mohd Nassir, Che Mohd Nasril, Abdul Hamid, Hafizah, Hambali, Aqilah, Abd Manan, Nizar, Mehat, Muhammad Zulfadli, Ismail, Nurul Iman, Mustapha, Muzaimi
Format: Article
Published: LIDSEN Publishing 2022
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author Che Mohd Nassir, Che Mohd Nasril
Abdul Hamid, Hafizah
Hambali, Aqilah
Abd Manan, Nizar
Mehat, Muhammad Zulfadli
Ismail, Nurul Iman
Mustapha, Muzaimi
author_facet Che Mohd Nassir, Che Mohd Nasril
Abdul Hamid, Hafizah
Hambali, Aqilah
Abd Manan, Nizar
Mehat, Muhammad Zulfadli
Ismail, Nurul Iman
Mustapha, Muzaimi
author_sort Che Mohd Nassir, Che Mohd Nasril
collection UPM
description The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the prevention of illnesses, including cardiocerebrovascular disease. Cerebral small vessel disease (CSVD) is one of the major risk factors for diseases such as stroke, dementia, Alzheimer’s disease, and Parkinson’s disease. CSVD is prevalent with aging and the presence of vascular risk factors. Its most common deleterious effect on the brain parenchyma is a neurological problem, causing a spectrum of subtle clinical manifestations such as neurocognitive dysfunction, emotional or behavioral disturbances, and gait dysfunction. Moreover, the pathological mechanisms and preventive strategies for CSVD remain elusive, which is reflected in the continued lack of effective therapeutic and preventive therapies. Given the growing literature on honey and its compounds as a superfood-based preventive measure, this narrative review highlights the neuroprotective potentials of honey and its compounds in relation to the current understanding of CSVD pathomechanism.
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institution Universiti Putra Malaysia
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spelling upm.eprints-1023022023-05-22T08:18:01Z http://psasir.upm.edu.my/id/eprint/102302/ Neuroprotective potentials of honey for cerebral small vessel disease Che Mohd Nassir, Che Mohd Nasril Abdul Hamid, Hafizah Hambali, Aqilah Abd Manan, Nizar Mehat, Muhammad Zulfadli Ismail, Nurul Iman Mustapha, Muzaimi The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the prevention of illnesses, including cardiocerebrovascular disease. Cerebral small vessel disease (CSVD) is one of the major risk factors for diseases such as stroke, dementia, Alzheimer’s disease, and Parkinson’s disease. CSVD is prevalent with aging and the presence of vascular risk factors. Its most common deleterious effect on the brain parenchyma is a neurological problem, causing a spectrum of subtle clinical manifestations such as neurocognitive dysfunction, emotional or behavioral disturbances, and gait dysfunction. Moreover, the pathological mechanisms and preventive strategies for CSVD remain elusive, which is reflected in the continued lack of effective therapeutic and preventive therapies. Given the growing literature on honey and its compounds as a superfood-based preventive measure, this narrative review highlights the neuroprotective potentials of honey and its compounds in relation to the current understanding of CSVD pathomechanism. LIDSEN Publishing 2022-11-14 Article PeerReviewed Che Mohd Nassir, Che Mohd Nasril and Abdul Hamid, Hafizah and Hambali, Aqilah and Abd Manan, Nizar and Mehat, Muhammad Zulfadli and Ismail, Nurul Iman and Mustapha, Muzaimi (2022) Neuroprotective potentials of honey for cerebral small vessel disease. OBM Neurobiology, 6 (39). pp. 1-39. ISSN 2573-4407 https://www.lidsen.com/journals/neurobiology/neurobiology-06-04-144 10.21926/obm.neurobiol.2204144
spellingShingle Che Mohd Nassir, Che Mohd Nasril
Abdul Hamid, Hafizah
Hambali, Aqilah
Abd Manan, Nizar
Mehat, Muhammad Zulfadli
Ismail, Nurul Iman
Mustapha, Muzaimi
Neuroprotective potentials of honey for cerebral small vessel disease
title Neuroprotective potentials of honey for cerebral small vessel disease
title_full Neuroprotective potentials of honey for cerebral small vessel disease
title_fullStr Neuroprotective potentials of honey for cerebral small vessel disease
title_full_unstemmed Neuroprotective potentials of honey for cerebral small vessel disease
title_short Neuroprotective potentials of honey for cerebral small vessel disease
title_sort neuroprotective potentials of honey for cerebral small vessel disease
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