Yeast inhibitive assay for anionic heavy metals: a review
One of the most common types of pollution that has a negative impact on the biotic community in aquatic habitats is heavy metal poisoning of the water. Both essential and non-essential heavy metals can be toxic to living things if their concentrations are too high for their bioavailability. Altho...
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| Format: | Article |
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Hibiscus Publisher
2022
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| _version_ | 1825938744200396800 |
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| author | Mohd Sadli, Farah Najieha Ammer, Masyitah Husna Shukor, Mohd Yunus |
| author_facet | Mohd Sadli, Farah Najieha Ammer, Masyitah Husna Shukor, Mohd Yunus |
| author_sort | Mohd Sadli, Farah Najieha |
| collection | UPM |
| description | One of the most common types of pollution that has a negative impact on the biotic community
in aquatic habitats is heavy metal poisoning of the water. Both essential and non-essential heavy
metals can be toxic to living things if their concentrations are too high for their bioavailability.
Although the toxicity of heavy metals, and especially anionic metal ions, is better known than
that of cationic metal ions, it is just as toxic, if not more so. The focus of this review is on the
usefulness of eukaryotic organisms like yeast, Saccharomyces cerevisiae, for toxicity assessment
because they can be easily maintained and developed in controlled circumstances, thereby
avoiding variability issues that arise when employing more complex organisms. Recent research
has shown that the majority of cellular MTT reduction occurs outside of the mitochondrial inner
membrane, and that this reduction is dependent on NADH and NADPH but is resistant to
respiratory chain inhibitors. |
| first_indexed | 2024-03-06T11:17:47Z |
| format | Article |
| id | upm.eprints-102653 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:17:47Z |
| publishDate | 2022 |
| publisher | Hibiscus Publisher |
| record_format | dspace |
| spelling | upm.eprints-1026532024-02-08T05:02:08Z http://psasir.upm.edu.my/id/eprint/102653/ Yeast inhibitive assay for anionic heavy metals: a review Mohd Sadli, Farah Najieha Ammer, Masyitah Husna Shukor, Mohd Yunus One of the most common types of pollution that has a negative impact on the biotic community in aquatic habitats is heavy metal poisoning of the water. Both essential and non-essential heavy metals can be toxic to living things if their concentrations are too high for their bioavailability. Although the toxicity of heavy metals, and especially anionic metal ions, is better known than that of cationic metal ions, it is just as toxic, if not more so. The focus of this review is on the usefulness of eukaryotic organisms like yeast, Saccharomyces cerevisiae, for toxicity assessment because they can be easily maintained and developed in controlled circumstances, thereby avoiding variability issues that arise when employing more complex organisms. Recent research has shown that the majority of cellular MTT reduction occurs outside of the mitochondrial inner membrane, and that this reduction is dependent on NADH and NADPH but is resistant to respiratory chain inhibitors. Hibiscus Publisher 2022-07 Article PeerReviewed Mohd Sadli, Farah Najieha and Ammer, Masyitah Husna and Shukor, Mohd Yunus (2022) Yeast inhibitive assay for anionic heavy metals: a review. Bioremediation Science and Technology Research, 10 (1). 30 - 36. ISSN 2289-5892 https://journal.hibiscuspublisher.com/index.php/BSTR/article/view/686 10.54987/bstr.v10i1.686 |
| spellingShingle | Mohd Sadli, Farah Najieha Ammer, Masyitah Husna Shukor, Mohd Yunus Yeast inhibitive assay for anionic heavy metals: a review |
| title | Yeast inhibitive assay for anionic heavy metals: a review |
| title_full | Yeast inhibitive assay for anionic heavy metals: a review |
| title_fullStr | Yeast inhibitive assay for anionic heavy metals: a review |
| title_full_unstemmed | Yeast inhibitive assay for anionic heavy metals: a review |
| title_short | Yeast inhibitive assay for anionic heavy metals: a review |
| title_sort | yeast inhibitive assay for anionic heavy metals a review |
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