Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study
Introduction: Non-adherence to antihypertensive medications is a leading cause of uncontrolled hypertension and its complications. However, data on the factors associated with non-adherence to antihypertensive medications in the communities of Sarawak, Malaysia, are limited. This study aimed to exam...
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| Format: | Article |
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Academy of Family Physicians of Malaysia
2022
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| author | Thew, Hui Zhu Ching, Siew Mooi Lim, Hooi Min Anak Mos, Mike Hitler Tze, Lorna Chin Kin Low, Kui Feng Shaari, Nurdarlina Lin, Jody Yii Sze Lee, Kai Wei Ramachandran, Vasudevan |
| author_facet | Thew, Hui Zhu Ching, Siew Mooi Lim, Hooi Min Anak Mos, Mike Hitler Tze, Lorna Chin Kin Low, Kui Feng Shaari, Nurdarlina Lin, Jody Yii Sze Lee, Kai Wei Ramachandran, Vasudevan |
| author_sort | Thew, Hui Zhu |
| collection | UPM |
| description | Introduction: Non-adherence to antihypertensive medications is a leading cause of uncontrolled hypertension and its complications. However, data on the factors associated with non-adherence to antihypertensive medications in the communities of Sarawak, Malaysia, are limited. This study aimed to examine the prevalence and determinants of medication non-adherence among patients with uncontrolled hypertension.
Methods: A cross-sectional study was conducted using the systematic sampling method in four government primary healthcare clinics in Sarawak. A self-administered questionnaire was used to obtain socio-demographic data and evaluate non-adherence. Blood pressure was measured, and relevant clinical variables were collected from medical records. Multivariate logistic regression was used to determine the determinants of medication non-adherence.
Results: A total of 488 patients with uncontrolled hypertension were enrolled in this study. The prevalence of medication non-adherence was 39.3%. There were four predictors of medication non-adherence among the patients with uncontrolled hypertension: tertiary educational level (odds ratio [OR]=4.21, 95% confidence interval [CI]=1.67–10.61, P=0.010), complementary alternative medication (OR=2.03, 95% CI=1.12–3.69, P=0.020), non-usage of calcium channel blockers (OR=1.57, 95% CI=1.02–2.41, P=0.039) and 1 mmHg increase in the systolic blood pressure (OR=1.03, 95% CI=1.00–1.05, P=0.006).
Conclusion: Because of the high prevalence of medication non-adherence among patients with uncontrolled hypertension, primary care physicians should be more vigilant in identifying those at risk of being non-adherent. Early intervention should be conducted to address non-adherence for blood pressure control. |
| first_indexed | 2024-09-25T03:37:13Z |
| format | Article |
| id | upm.eprints-102870 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-09-25T03:37:13Z |
| publishDate | 2022 |
| publisher | Academy of Family Physicians of Malaysia |
| record_format | dspace |
| spelling | upm.eprints-1028702024-06-30T15:13:12Z http://psasir.upm.edu.my/id/eprint/102870/ Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study Thew, Hui Zhu Ching, Siew Mooi Lim, Hooi Min Anak Mos, Mike Hitler Tze, Lorna Chin Kin Low, Kui Feng Shaari, Nurdarlina Lin, Jody Yii Sze Lee, Kai Wei Ramachandran, Vasudevan Introduction: Non-adherence to antihypertensive medications is a leading cause of uncontrolled hypertension and its complications. However, data on the factors associated with non-adherence to antihypertensive medications in the communities of Sarawak, Malaysia, are limited. This study aimed to examine the prevalence and determinants of medication non-adherence among patients with uncontrolled hypertension. Methods: A cross-sectional study was conducted using the systematic sampling method in four government primary healthcare clinics in Sarawak. A self-administered questionnaire was used to obtain socio-demographic data and evaluate non-adherence. Blood pressure was measured, and relevant clinical variables were collected from medical records. Multivariate logistic regression was used to determine the determinants of medication non-adherence. Results: A total of 488 patients with uncontrolled hypertension were enrolled in this study. The prevalence of medication non-adherence was 39.3%. There were four predictors of medication non-adherence among the patients with uncontrolled hypertension: tertiary educational level (odds ratio [OR]=4.21, 95% confidence interval [CI]=1.67–10.61, P=0.010), complementary alternative medication (OR=2.03, 95% CI=1.12–3.69, P=0.020), non-usage of calcium channel blockers (OR=1.57, 95% CI=1.02–2.41, P=0.039) and 1 mmHg increase in the systolic blood pressure (OR=1.03, 95% CI=1.00–1.05, P=0.006). Conclusion: Because of the high prevalence of medication non-adherence among patients with uncontrolled hypertension, primary care physicians should be more vigilant in identifying those at risk of being non-adherent. Early intervention should be conducted to address non-adherence for blood pressure control. Academy of Family Physicians of Malaysia 2022 Article PeerReviewed Thew, Hui Zhu and Ching, Siew Mooi and Lim, Hooi Min and Anak Mos, Mike Hitler and Tze, Lorna Chin Kin and Low, Kui Feng and Shaari, Nurdarlina and Lin, Jody Yii Sze and Lee, Kai Wei and Ramachandran, Vasudevan (2022) Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study. Malaysian family physician, 17 (3). pp. 128-136. ISSN 1985-207X,1985-2274 https://e-mfp.org/wp-content/uploads/v17n3-OA-Prevalence-and-determinants-of-medications.pdf 10.51866/oa.182 |
| spellingShingle | Thew, Hui Zhu Ching, Siew Mooi Lim, Hooi Min Anak Mos, Mike Hitler Tze, Lorna Chin Kin Low, Kui Feng Shaari, Nurdarlina Lin, Jody Yii Sze Lee, Kai Wei Ramachandran, Vasudevan Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title | Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title_full | Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title_fullStr | Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title_full_unstemmed | Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title_short | Prevalence and determinants of medications non-adherence among patients with uncontrolled hypertension in primary care setting in Sarawak, Malaysia: a cross-sectional study |
| title_sort | prevalence and determinants of medications non adherence among patients with uncontrolled hypertension in primary care setting in sarawak malaysia a cross sectional study |
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