Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients

Introduction: Domains of adherence and non-adherence to hypertensive medications have not been extensively documented in Malaysia due to the absence of theoretically driven and culturally appropriate measurement tools, leading to a poor understanding of the adherence and underlying factors. We aim...

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Main Authors: Yew, Sheng Qian, Mohd Nazan, Ahmad Iqmer Nashriq, Tan, Kit Aun
Format: Article
Published: Universiti Putra Malaysia 2022
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author Yew, Sheng Qian
Mohd Nazan, Ahmad Iqmer Nashriq
Tan, Kit Aun
author_facet Yew, Sheng Qian
Mohd Nazan, Ahmad Iqmer Nashriq
Tan, Kit Aun
author_sort Yew, Sheng Qian
collection UPM
description Introduction: Domains of adherence and non-adherence to hypertensive medications have not been extensively documented in Malaysia due to the absence of theoretically driven and culturally appropriate measurement tools, leading to a poor understanding of the adherence and underlying factors. We aim to identify these domains in Malaysian hypertensive patients and subsequently apply the findings to develop and validate the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Methods: This study has an exploratory mixed-methods design. In Phase 1, we will recruit hypertensive patients from two health clinics to participate in a semi-structured interview. Recruitment of participants will terminate once thematic saturation is achieved. Coding and thematic analyses will be performed to identify the domains of adherence and non-adherence to anti-hypertensive medications. In Phase 2, based on the domains generated from Phase 1, we will develop the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Four hundred hypertensive patients will be randomly selected. Data from 200 participants (serving as the calibration sample) will be subjected to exploratory factor analysis while data from additional 200 participants (serving as the validation sample) will be subjected to confirmatory factor analysis. Factor structure, predictive validity, and reliability of the MAANS will be statistically tested. Discussion: With the presence of the MAANS, health care providers can gather crucial information regarding barriers and facilitators to hypertensive treatment adherence and design effective health promotion programmes to reduce complications of uncontrolled hypertension.
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spelling upm.eprints-1033472023-06-16T07:40:14Z http://psasir.upm.edu.my/id/eprint/103347/ Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients Yew, Sheng Qian Mohd Nazan, Ahmad Iqmer Nashriq Tan, Kit Aun Introduction: Domains of adherence and non-adherence to hypertensive medications have not been extensively documented in Malaysia due to the absence of theoretically driven and culturally appropriate measurement tools, leading to a poor understanding of the adherence and underlying factors. We aim to identify these domains in Malaysian hypertensive patients and subsequently apply the findings to develop and validate the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Methods: This study has an exploratory mixed-methods design. In Phase 1, we will recruit hypertensive patients from two health clinics to participate in a semi-structured interview. Recruitment of participants will terminate once thematic saturation is achieved. Coding and thematic analyses will be performed to identify the domains of adherence and non-adherence to anti-hypertensive medications. In Phase 2, based on the domains generated from Phase 1, we will develop the Malaysian Anti-Hypertensive Agents Non-Adherence Scale (MAANS). Four hundred hypertensive patients will be randomly selected. Data from 200 participants (serving as the calibration sample) will be subjected to exploratory factor analysis while data from additional 200 participants (serving as the validation sample) will be subjected to confirmatory factor analysis. Factor structure, predictive validity, and reliability of the MAANS will be statistically tested. Discussion: With the presence of the MAANS, health care providers can gather crucial information regarding barriers and facilitators to hypertensive treatment adherence and design effective health promotion programmes to reduce complications of uncontrolled hypertension. Universiti Putra Malaysia 2022 Article PeerReviewed Yew, Sheng Qian and Mohd Nazan, Ahmad Iqmer Nashriq and Tan, Kit Aun (2022) Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients. Malaysian Journal of Medicine and Health Sciences, 18 (6). 332 - 339. ISSN 2636-9346 https://medic.upm.edu.my/jurnal_kami/volume_18_2022/mjmhs_vol18_no_6_november_2022-70224 10.47836/mjmhs18.6.42
spellingShingle Yew, Sheng Qian
Mohd Nazan, Ahmad Iqmer Nashriq
Tan, Kit Aun
Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title_full Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title_fullStr Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title_full_unstemmed Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title_short Study protocol of a mixed-methods study to develop and validate the Malaysian anti-hypertensive agents non-adherence scale in hypertensive patients
title_sort study protocol of a mixed methods study to develop and validate the malaysian anti hypertensive agents non adherence scale in hypertensive patients
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