Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks
Tuberculosis (TB) is a globally important reemerging disease that is chronic, multi host infection caused by Mycobacterium tuberculosis complex (MTBC), which causes disease in livestock, wildlife and zoonotic TB in humans. Twelve (n=12) different species of NHPs were screened for MTBC and MAC in Zo...
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| Format: | Article |
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Faculty Of Veterinary Science, University Of Agriculture
2022
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| author | Lekko, Yusuf Madaki Ooi, Peck Toung Omar, Sharina Mazlan, Mazlina Sivapalan, Nyanavelan Ramanoon, Siti Zubaidah Abdullah Jesse, Faez Firdaus Jasni, Sabri Che Amat, Azlan |
| author_facet | Lekko, Yusuf Madaki Ooi, Peck Toung Omar, Sharina Mazlan, Mazlina Sivapalan, Nyanavelan Ramanoon, Siti Zubaidah Abdullah Jesse, Faez Firdaus Jasni, Sabri Che Amat, Azlan |
| author_sort | Lekko, Yusuf Madaki |
| collection | UPM |
| description | Tuberculosis (TB) is a globally important reemerging disease that is chronic, multi host infection caused by Mycobacterium tuberculosis complex (MTBC), which causes disease in livestock, wildlife and zoonotic TB in humans. Twelve (n=12)
different species of NHPs were screened for MTBC and MAC in Zoo Melaka, Malaysia. The surveillance of MTBC and MAC was through the application of skin test, serology and PCR. The results showed two orangutan Pongo spp. (16.7%) were
reactive to skin test with orangutan A showing obvious swelling of eyelids with drooping and varying degrees of erythema and orangutan B with moderate swelling of the eyelids with drooping and without erythema. For the antibody detection against MTBC, these two orangutans were positive by serology (16.7%), all other NHPs were antibody negative. Polymerase chain reaction from the blood of all NHPs was
negative for the MTBC, however, all samples from blood and pharyngeal swab were PCR positive for MAC. In conclusion MAC was detected in captive NHPs population probably due to exposure to the environment without completely discriminating MTBC. |
| first_indexed | 2024-03-06T11:18:18Z |
| format | Article |
| id | upm.eprints-103371 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T11:18:18Z |
| publishDate | 2022 |
| publisher | Faculty Of Veterinary Science, University Of Agriculture |
| record_format | dspace |
| spelling | upm.eprints-1033712023-06-14T02:41:13Z http://psasir.upm.edu.my/id/eprint/103371/ Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks Lekko, Yusuf Madaki Ooi, Peck Toung Omar, Sharina Mazlan, Mazlina Sivapalan, Nyanavelan Ramanoon, Siti Zubaidah Abdullah Jesse, Faez Firdaus Jasni, Sabri Che Amat, Azlan Tuberculosis (TB) is a globally important reemerging disease that is chronic, multi host infection caused by Mycobacterium tuberculosis complex (MTBC), which causes disease in livestock, wildlife and zoonotic TB in humans. Twelve (n=12) different species of NHPs were screened for MTBC and MAC in Zoo Melaka, Malaysia. The surveillance of MTBC and MAC was through the application of skin test, serology and PCR. The results showed two orangutan Pongo spp. (16.7%) were reactive to skin test with orangutan A showing obvious swelling of eyelids with drooping and varying degrees of erythema and orangutan B with moderate swelling of the eyelids with drooping and without erythema. For the antibody detection against MTBC, these two orangutans were positive by serology (16.7%), all other NHPs were antibody negative. Polymerase chain reaction from the blood of all NHPs was negative for the MTBC, however, all samples from blood and pharyngeal swab were PCR positive for MAC. In conclusion MAC was detected in captive NHPs population probably due to exposure to the environment without completely discriminating MTBC. Faculty Of Veterinary Science, University Of Agriculture 2022 Article PeerReviewed Lekko, Yusuf Madaki and Ooi, Peck Toung and Omar, Sharina and Mazlan, Mazlina and Sivapalan, Nyanavelan and Ramanoon, Siti Zubaidah and Abdullah Jesse, Faez Firdaus and Jasni, Sabri and Che Amat, Azlan (2022) Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks. Pakistan Veterinary Journal, 42 (3). 340 - 345. ISSN 0253-8318 http://www.pvj.com.pk/archive/Volume_42_Issue_3_2022.htm 10.29261/pakvetj/2022.057 |
| spellingShingle | Lekko, Yusuf Madaki Ooi, Peck Toung Omar, Sharina Mazlan, Mazlina Sivapalan, Nyanavelan Ramanoon, Siti Zubaidah Abdullah Jesse, Faez Firdaus Jasni, Sabri Che Amat, Azlan Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title | Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title_full | Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title_fullStr | Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title_full_unstemmed | Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title_short | Surveillance and detection of Mycobacterium tuberculosis complex and Mycobacterium avium complex in captive non-human primates in zoological parks |
| title_sort | surveillance and detection of mycobacterium tuberculosis complex and mycobacterium avium complex in captive non human primates in zoological parks |
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