Fetal acalvaria with lateral cleft lip and palate: a rare presentation
We report a case of acalvaria diagnosed prenatally via ultrasound and MRI. Acalvaria is a rare, fatal congenital condition characterized by the absence of flat bones of the cranial vault, dura mater, and its associated muscles with an intact central nervous system. A 41-year-old gravida 5, para 2 +...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/105870/1/1-s2.0-S1930043323007781-main.pdf |
| _version_ | 1825939273147219968 |
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| author | Mohd Jamil, Amilia Afzan Chua, Wang Ching Valayudham, Vairavan Ramesh Abu Hassan, Hasyma Abdul Jalal, Hamidah |
| author_facet | Mohd Jamil, Amilia Afzan Chua, Wang Ching Valayudham, Vairavan Ramesh Abu Hassan, Hasyma Abdul Jalal, Hamidah |
| author_sort | Mohd Jamil, Amilia Afzan |
| collection | UPM |
| description | We report a case of acalvaria diagnosed prenatally via ultrasound and MRI. Acalvaria is a rare, fatal congenital condition characterized by the absence of flat bones of the cranial vault, dura mater, and its associated muscles with an intact central nervous system. A 41-year-old gravida 5, para 2 + 2A, presented to us at 26 weeks gestation age (GA) with ultrasound findings of a fragile and hypomineralized skull in the fetus. The patient was not keen on whole-axon sequencing. Fetus magnetic resonance imaging (MRI) revealed large cutaneous/skull nonvisualization of the fetus skull, possibly acrania without anencephaly. She delivered via cesarean section at 37 weeks because of two previous cesarean sections. A female infant weighing 2650 g was born with an intact sac to minimize excessive external pressure to the brain tissue. A diagnosis of acalvaria with bilateral lateral cleft lip and palate was made postdelivery. The infant was managed conservatively per multidisciplinary discussion and expired 3 weeks later. |
| first_indexed | 2024-04-09T03:51:43Z |
| format | Article |
| id | upm.eprints-105870 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-09-25T03:38:32Z |
| publishDate | 2024 |
| publisher | Elsevier Inc. |
| record_format | dspace |
| spelling | upm.eprints-1058702024-07-15T04:19:53Z http://psasir.upm.edu.my/id/eprint/105870/ Fetal acalvaria with lateral cleft lip and palate: a rare presentation Mohd Jamil, Amilia Afzan Chua, Wang Ching Valayudham, Vairavan Ramesh Abu Hassan, Hasyma Abdul Jalal, Hamidah We report a case of acalvaria diagnosed prenatally via ultrasound and MRI. Acalvaria is a rare, fatal congenital condition characterized by the absence of flat bones of the cranial vault, dura mater, and its associated muscles with an intact central nervous system. A 41-year-old gravida 5, para 2 + 2A, presented to us at 26 weeks gestation age (GA) with ultrasound findings of a fragile and hypomineralized skull in the fetus. The patient was not keen on whole-axon sequencing. Fetus magnetic resonance imaging (MRI) revealed large cutaneous/skull nonvisualization of the fetus skull, possibly acrania without anencephaly. She delivered via cesarean section at 37 weeks because of two previous cesarean sections. A female infant weighing 2650 g was born with an intact sac to minimize excessive external pressure to the brain tissue. A diagnosis of acalvaria with bilateral lateral cleft lip and palate was made postdelivery. The infant was managed conservatively per multidisciplinary discussion and expired 3 weeks later. Elsevier Inc. 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/105870/1/1-s2.0-S1930043323007781-main.pdf Mohd Jamil, Amilia Afzan and Chua, Wang Ching and Valayudham, Vairavan Ramesh and Abu Hassan, Hasyma and Abdul Jalal, Hamidah (2024) Fetal acalvaria with lateral cleft lip and palate: a rare presentation. Radiology Case Reports, 19 (1). pp. 374-377. ISSN 1930-0433 https://www.sciencedirect.com/science/article/pii/S1930043323007781 10.1016/j.radcr.2023.10.036 |
| spellingShingle | Mohd Jamil, Amilia Afzan Chua, Wang Ching Valayudham, Vairavan Ramesh Abu Hassan, Hasyma Abdul Jalal, Hamidah Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title | Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title_full | Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title_fullStr | Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title_full_unstemmed | Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title_short | Fetal acalvaria with lateral cleft lip and palate: a rare presentation |
| title_sort | fetal acalvaria with lateral cleft lip and palate a rare presentation |
| url | http://psasir.upm.edu.my/id/eprint/105870/1/1-s2.0-S1930043323007781-main.pdf |
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