A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications

Encapsulation of bioactive compound has some encountered issues associated particularly to their mode of fabrication, design, and biodegradability. For these reasons, selecting appropriate coating materials like hydroxyl cellulose has several advantages such as modification of moisture, crystal grow...

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Main Authors: Saadi, Sami, Nacer, Nor Elhouda, Chenaker, Hichem, Ariffin, Abdul Azis, Ghazali, Hasanah Mohd, Saari, Nazamid, Mohammed, Abdulkarim Sabo, Anwar, Farooq, Hamid, Azizah Abdul
Format: Article
Published: Springer 2023
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author Saadi, Sami
Nacer, Nor Elhouda
Chenaker, Hichem
Ariffin, Abdul Azis
Ghazali, Hasanah Mohd
Saari, Nazamid
Mohammed, Abdulkarim Sabo
Anwar, Farooq
Hamid, Azizah Abdul
author_facet Saadi, Sami
Nacer, Nor Elhouda
Chenaker, Hichem
Ariffin, Abdul Azis
Ghazali, Hasanah Mohd
Saari, Nazamid
Mohammed, Abdulkarim Sabo
Anwar, Farooq
Hamid, Azizah Abdul
author_sort Saadi, Sami
collection UPM
description Encapsulation of bioactive compound has some encountered issues associated particularly to their mode of fabrication, design, and biodegradability. For these reasons, selecting appropriate coating materials like hydroxyl cellulose has several advantages such as modification of moisture, crystal growth, and viscosity. In addition, starches, maltodextrins, whey proteins, chitosan, zein/pectin, and alginates are considered an important coating materials used during microencapsulation processing steps. Thus, the variability in the hydrophilicity, lipophilicity and chargeability levels of those coating materials along with the encapsulation is considered among the molecular aspects in forming genius emulsion vesicles, microgels, solid lipid nanoparticles, liposomes, or core shell nanoparticles. These encapsulation designs are capable in promoting variable physicochemical and therapeutic features such as intra-atomic dimensions, dispersed volumes, release kinetics, and stability levels. Under these desired structural and molecular parameters, in addition to proper optimization of processing conditions, perfect microcarriers and microcapsules could be achieved. Moreover, appropriate control of copolymerization and crystallization of the coating materials with some antagonistic pharmaceutical drugs needs special emphasize. In general, this manuscript reviews various important aspects of structured materials used along with their production and potential uses for enhancing targeted delivery and release of therapeutic foods.
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spelling upm.eprints-1067002024-09-26T07:48:06Z http://psasir.upm.edu.my/id/eprint/106700/ A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications Saadi, Sami Nacer, Nor Elhouda Chenaker, Hichem Ariffin, Abdul Azis Ghazali, Hasanah Mohd Saari, Nazamid Mohammed, Abdulkarim Sabo Anwar, Farooq Hamid, Azizah Abdul Encapsulation of bioactive compound has some encountered issues associated particularly to their mode of fabrication, design, and biodegradability. For these reasons, selecting appropriate coating materials like hydroxyl cellulose has several advantages such as modification of moisture, crystal growth, and viscosity. In addition, starches, maltodextrins, whey proteins, chitosan, zein/pectin, and alginates are considered an important coating materials used during microencapsulation processing steps. Thus, the variability in the hydrophilicity, lipophilicity and chargeability levels of those coating materials along with the encapsulation is considered among the molecular aspects in forming genius emulsion vesicles, microgels, solid lipid nanoparticles, liposomes, or core shell nanoparticles. These encapsulation designs are capable in promoting variable physicochemical and therapeutic features such as intra-atomic dimensions, dispersed volumes, release kinetics, and stability levels. Under these desired structural and molecular parameters, in addition to proper optimization of processing conditions, perfect microcarriers and microcapsules could be achieved. Moreover, appropriate control of copolymerization and crystallization of the coating materials with some antagonistic pharmaceutical drugs needs special emphasize. In general, this manuscript reviews various important aspects of structured materials used along with their production and potential uses for enhancing targeted delivery and release of therapeutic foods. Springer 2023-08-24 Article PeerReviewed Saadi, Sami and Nacer, Nor Elhouda and Chenaker, Hichem and Ariffin, Abdul Azis and Ghazali, Hasanah Mohd and Saari, Nazamid and Mohammed, Abdulkarim Sabo and Anwar, Farooq and Hamid, Azizah Abdul (2023) A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications. European Food Research and Technology, 249 (12). 3123 - 3139. ISSN 1438-2377; ESSN: 1438-2385 https://link.springer.com/article/10.1007/s00217-023-04354-2#citeas 10.1007/s00217-023-04354-2
spellingShingle Saadi, Sami
Nacer, Nor Elhouda
Chenaker, Hichem
Ariffin, Abdul Azis
Ghazali, Hasanah Mohd
Saari, Nazamid
Mohammed, Abdulkarim Sabo
Anwar, Farooq
Hamid, Azizah Abdul
A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title_full A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title_fullStr A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title_full_unstemmed A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title_short A review on trends in microencapsulation of bioactive compounds: coating materials, design, and applications
title_sort review on trends in microencapsulation of bioactive compounds coating materials design and applications
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