Biodegradable synthetic polymer in orthopaedic application: a review
Every year, many people suffer from bone fractures because of accidents or diseases. Majority of these fractures are too complicated to be treated with conventional medicine and must be mended surgically using non-degradable metal inserts. Such treatment may result in refusal and protection against...
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| Format: | Article |
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Elsevier Bv
2023
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| _version_ | 1817927415576395776 |
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| author | Al-Shalawi, Faisal Dakhelallah Azmah Hanim, M. A. Ariffin, M. K. A. Looi Seng Kim, Collin Brabazon, Dermot Calin, Recep Al-Osaimi, Maha Obaid |
| author_facet | Al-Shalawi, Faisal Dakhelallah Azmah Hanim, M. A. Ariffin, M. K. A. Looi Seng Kim, Collin Brabazon, Dermot Calin, Recep Al-Osaimi, Maha Obaid |
| author_sort | Al-Shalawi, Faisal Dakhelallah |
| collection | UPM |
| description | Every year, many people suffer from bone fractures because of accidents or diseases. Majority of these fractures are too complicated to be treated with conventional medicine and must be mended surgically using non-degradable metal inserts. Such treatment may result in refusal and protection against stress, but may also require another surgical procedure to get rid of the metal inserts. Additionally, biodegradable metals that can readily erode inside the human body come with certain complications. These aspects prompted scientists to find alternatives to metals. Some researchers began to focus on the field of polymers which have shown significant promise in replacing metals. In orthopaedics, degradable polymeric fixation appliances are being studied to substitute metallic implants, eliminating stress protection and avoiding another implant removal surgery. The new generation of bioabsorbable and degradable polymeric implants are free from toxic and mutagenic effects. Nevertheless, these implants have several issues, including mechanical stiffness and strength limitations, unfavourable tissue responses, foreign body reactions, the late response of degraded tissue, and infection due to crystallinity and hydrophobicity. This review discusses the alternative synthetic polymer implant materials available that can be employed and their properties. |
| first_indexed | 2024-12-09T02:18:05Z |
| format | Article |
| id | upm.eprints-106880 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-12-09T02:18:05Z |
| publishDate | 2023 |
| publisher | Elsevier Bv |
| record_format | dspace |
| spelling | upm.eprints-1068802024-10-11T08:21:23Z http://psasir.upm.edu.my/id/eprint/106880/ Biodegradable synthetic polymer in orthopaedic application: a review Al-Shalawi, Faisal Dakhelallah Azmah Hanim, M. A. Ariffin, M. K. A. Looi Seng Kim, Collin Brabazon, Dermot Calin, Recep Al-Osaimi, Maha Obaid Every year, many people suffer from bone fractures because of accidents or diseases. Majority of these fractures are too complicated to be treated with conventional medicine and must be mended surgically using non-degradable metal inserts. Such treatment may result in refusal and protection against stress, but may also require another surgical procedure to get rid of the metal inserts. Additionally, biodegradable metals that can readily erode inside the human body come with certain complications. These aspects prompted scientists to find alternatives to metals. Some researchers began to focus on the field of polymers which have shown significant promise in replacing metals. In orthopaedics, degradable polymeric fixation appliances are being studied to substitute metallic implants, eliminating stress protection and avoiding another implant removal surgery. The new generation of bioabsorbable and degradable polymeric implants are free from toxic and mutagenic effects. Nevertheless, these implants have several issues, including mechanical stiffness and strength limitations, unfavourable tissue responses, foreign body reactions, the late response of degraded tissue, and infection due to crystallinity and hydrophobicity. This review discusses the alternative synthetic polymer implant materials available that can be employed and their properties. Elsevier Bv 2023 Article PeerReviewed Al-Shalawi, Faisal Dakhelallah and Azmah Hanim, M. A. and Ariffin, M. K. A. and Looi Seng Kim, Collin and Brabazon, Dermot and Calin, Recep and Al-Osaimi, Maha Obaid (2023) Biodegradable synthetic polymer in orthopaedic application: a review. Materials Today, 74 (pt.3). pp. 540-546. ISSN 2214-7853 https://linkinghub.elsevier.com/retrieve/pii/S221478532207626X 10.1016/j.matpr.2022.12.254 |
| spellingShingle | Al-Shalawi, Faisal Dakhelallah Azmah Hanim, M. A. Ariffin, M. K. A. Looi Seng Kim, Collin Brabazon, Dermot Calin, Recep Al-Osaimi, Maha Obaid Biodegradable synthetic polymer in orthopaedic application: a review |
| title | Biodegradable synthetic polymer in orthopaedic application: a review |
| title_full | Biodegradable synthetic polymer in orthopaedic application: a review |
| title_fullStr | Biodegradable synthetic polymer in orthopaedic application: a review |
| title_full_unstemmed | Biodegradable synthetic polymer in orthopaedic application: a review |
| title_short | Biodegradable synthetic polymer in orthopaedic application: a review |
| title_sort | biodegradable synthetic polymer in orthopaedic application a review |
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