Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region

Edoxaban, a once-daily, direct-acting oral anticoagulant, is approved to prevent stroke or systemic embolism in non-valvular atrial fibrillation (NVAF) and treat venous thromboembolism. The clinical benefit of edoxaban for stroke prevention in Asian patients with NVAF has been demonstrated in clinic...

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Main Authors: Bimbo Diaz, Alejandro, Chow, Jeremy, Fan, Kee Hoo, Kok, Wei Koh, Chin, Gary Keong Lee, Wee, Siong Teo, Venketasubramanian, Narayanaswamy, Chun, Chieh Wang, Mehta, Radhika
Format: Article
Language:English
Published: Bioexcel Publishing 2023
Online Access:http://psasir.upm.edu.my/id/eprint/107426/1/107426.pdf
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author Bimbo Diaz, Alejandro
Chow, Jeremy
Fan, Kee Hoo
Kok, Wei Koh
Chin, Gary Keong Lee
Wee, Siong Teo
Venketasubramanian, Narayanaswamy
Chun, Chieh Wang
Mehta, Radhika
author_facet Bimbo Diaz, Alejandro
Chow, Jeremy
Fan, Kee Hoo
Kok, Wei Koh
Chin, Gary Keong Lee
Wee, Siong Teo
Venketasubramanian, Narayanaswamy
Chun, Chieh Wang
Mehta, Radhika
author_sort Bimbo Diaz, Alejandro
collection UPM
description Edoxaban, a once-daily, direct-acting oral anticoagulant, is approved to prevent stroke or systemic embolism in non-valvular atrial fibrillation (NVAF) and treat venous thromboembolism. The clinical benefit of edoxaban for stroke prevention in Asian patients with NVAF has been demonstrated in clinical and real-world studies. We share early clinical experiences with once-daily edoxaban and discuss its evidence-based use in patients with NVAF in Southeast Asia through several cases of patients at high risk, including frail patients, elderly patients with multiple comorbidities and patients with increased bleeding risk. These cases demonstrate the effectiveness and safety of once-daily edoxaban in patients with NVAF in Southeast Asia.
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spelling upm.eprints-1074262024-11-04T02:35:08Z http://psasir.upm.edu.my/id/eprint/107426/ Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region Bimbo Diaz, Alejandro Chow, Jeremy Fan, Kee Hoo Kok, Wei Koh Chin, Gary Keong Lee Wee, Siong Teo Venketasubramanian, Narayanaswamy Chun, Chieh Wang Mehta, Radhika Edoxaban, a once-daily, direct-acting oral anticoagulant, is approved to prevent stroke or systemic embolism in non-valvular atrial fibrillation (NVAF) and treat venous thromboembolism. The clinical benefit of edoxaban for stroke prevention in Asian patients with NVAF has been demonstrated in clinical and real-world studies. We share early clinical experiences with once-daily edoxaban and discuss its evidence-based use in patients with NVAF in Southeast Asia through several cases of patients at high risk, including frail patients, elderly patients with multiple comorbidities and patients with increased bleeding risk. These cases demonstrate the effectiveness and safety of once-daily edoxaban in patients with NVAF in Southeast Asia. Bioexcel Publishing 2023-09-08 Article PeerReviewed text en cc_by_nc_nd_4 http://psasir.upm.edu.my/id/eprint/107426/1/107426.pdf Bimbo Diaz, Alejandro and Chow, Jeremy and Fan, Kee Hoo and Kok, Wei Koh and Chin, Gary Keong Lee and Wee, Siong Teo and Venketasubramanian, Narayanaswamy and Chun, Chieh Wang and Mehta, Radhika (2023) Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region. Drugs in Context, 12 (3). pp. 1-15. ISSN 1745-1981; eISSN: 1740-4398 https://www.drugsincontext.com/early-experiences-with-edoxaban-for-stroke-prevention-in-atrial-fibrillation-in-the-southeast-asia-region/ 10.7573/dic.2023-3-3
spellingShingle Bimbo Diaz, Alejandro
Chow, Jeremy
Fan, Kee Hoo
Kok, Wei Koh
Chin, Gary Keong Lee
Wee, Siong Teo
Venketasubramanian, Narayanaswamy
Chun, Chieh Wang
Mehta, Radhika
Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title_full Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title_fullStr Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title_full_unstemmed Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title_short Early experiences with edoxaban for stroke prevention in atrial fibrillation in the Southeast Asia region
title_sort early experiences with edoxaban for stroke prevention in atrial fibrillation in the southeast asia region
url http://psasir.upm.edu.my/id/eprint/107426/1/107426.pdf
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