Effect of secretion efficiency of mutant KRAS neoantigen by Lactococcus lactis on the immune response of a mucosal vaccine delivery vehicle targeting colorectal cancer
Colorectal cancer (CRC) is often caused by mutations in the KRAS oncogene, making KRAS neoantigens a promising vaccine candidate for immunotherapy. Secreting KRAS antigens using live Generally Recognized as Safe (GRAS) vaccine delivery hosts such as Lactococcus lactis is deemed to be an effective st...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/107528/1/Effect%20of%20secretion%20efficiency%20of%20mutant%20KRAS%20neoantigen%20by%20Lactococcus%20lactis.pdf |