The NLRP3 inflammasome in age-related cerebral small vessel disease manifestations: untying the innate immune response connection
In this narrative review, we present the evidence on nucleotide-binding and oligomerization (NOD) domain-like receptor (NLR) family pyrin domain (PYD)-containing 3 (NLRP3) inflammasome activation for its putative roles in the elusive pathomechanism of aging-related cerebral small vessel disease (CSV...
Main Authors: | Che Mohd Nassir, Che Mohd Nasril, Damodaran, Thenmoly, Ismail, Nurul Iman, Hashim, Sabarisah, Jaffer, Usman, Hamid, Hafizah Abdul, Mehat, Muhammad Zulfadli, Norazit, Anwar, Mustapha, Muzaimi |
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Format: | Article |
Language: | English |
Published: |
Multidisciplinary Digital Publishing Institute
2023
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Online Access: | http://psasir.upm.edu.my/id/eprint/108690/1/The%20NLRP3%20inflammasome%20in%20age-related%20cerebral.pdf |
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