In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset
Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in produci...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf |
| _version_ | 1825939664253485056 |
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| author | Zainudin, Robiatul Azilah Sabri, Suriana Salleh, Abu Bakar Abu, Arpah Raja Khairuddin, Raja Farhana Oslan, Siti Nurbaya |
| author_facet | Zainudin, Robiatul Azilah Sabri, Suriana Salleh, Abu Bakar Abu, Arpah Raja Khairuddin, Raja Farhana Oslan, Siti Nurbaya |
| author_sort | Zainudin, Robiatul Azilah |
| collection | UPM |
| description | Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in producing industrially important recombinant proteins. The species possesses high similarity to Candida albicans which may cause candidiasis. The industrial-benefiting M. guilliermondii strain SO has been underexplored for its virulence status. Thus, this study aimed to document the potential virulence factors through the comprehensive in silico analysis of M. guilliermondii strain SO genome. This analysis demonstrated the molecular characterization which could distinguish the pathogenicity status of M. guilliermondii. |
| first_indexed | 2024-12-09T02:20:49Z |
| format | Article |
| id | upm.eprints-108816 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-12-09T02:20:49Z |
| publishDate | 2023 |
| publisher | SpringerOpen |
| record_format | dspace |
| spelling | upm.eprints-1088162024-10-11T08:50:49Z http://psasir.upm.edu.my/id/eprint/108816/ In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset Zainudin, Robiatul Azilah Sabri, Suriana Salleh, Abu Bakar Abu, Arpah Raja Khairuddin, Raja Farhana Oslan, Siti Nurbaya Meyerozyma guilliermondii is a prospective yeast that has extensively contributed to the biotechnology sector. In 2015, M. guilliermondii strain SO which was isolated from spoiled orange has successfully been developed as an inducer-free expression system and attained a significant impact in producing industrially important recombinant proteins. The species possesses high similarity to Candida albicans which may cause candidiasis. The industrial-benefiting M. guilliermondii strain SO has been underexplored for its virulence status. Thus, this study aimed to document the potential virulence factors through the comprehensive in silico analysis of M. guilliermondii strain SO genome. This analysis demonstrated the molecular characterization which could distinguish the pathogenicity status of M. guilliermondii. SpringerOpen 2023-01-12 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf Zainudin, Robiatul Azilah and Sabri, Suriana and Salleh, Abu Bakar and Abu, Arpah and Raja Khairuddin, Raja Farhana and Oslan, Siti Nurbaya (2023) In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset. Egyptian Journal of Medical Human Genetics, 24 (6). art. no. 6. pp. 1-13. ISSN 1110-8630; eISSN: 2090-2441 https://jmhg.springeropen.com/articles/10.1186/s43042-023-00384-3 10.1186/s43042-023-00384-3 |
| spellingShingle | Zainudin, Robiatul Azilah Sabri, Suriana Salleh, Abu Bakar Abu, Arpah Raja Khairuddin, Raja Farhana Oslan, Siti Nurbaya In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title | In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title_full | In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title_fullStr | In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title_full_unstemmed | In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title_short | In silico identification of prospective virulence factors associated with candidiasis in Meyerozyma guilliermondii strain SO from genome dataset |
| title_sort | in silico identification of prospective virulence factors associated with candidiasis in meyerozyma guilliermondii strain so from genome dataset |
| url | http://psasir.upm.edu.my/id/eprint/108816/1/108816.pdf |
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