Quorum sensing signals: aquaculture risk factor
Bacteria produce several virulence factors and cause massive mortality in fish and crustaceans. Abundant quorum sensing (QS) signals and high cell density are essentially required for the production of such virulence factors. Although several strategies have been developed to control aquatic pathoge...
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Wiley
2023
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author | Priya, P. Snega Boopathi, Seenivasan Murugan, Raghul Haridevamuthu, B. Arshad, Aziz Arockiaraj, Jesu |
author_facet | Priya, P. Snega Boopathi, Seenivasan Murugan, Raghul Haridevamuthu, B. Arshad, Aziz Arockiaraj, Jesu |
author_sort | Priya, P. Snega |
collection | UPM |
description | Bacteria produce several virulence factors and cause massive mortality in fish and crustaceans. Abundant quorum sensing (QS) signals and high cell density are essentially required for the production of such virulence factors. Although several strategies have been developed to control aquatic pathogens through antibiotics and QS inhibition, the impact of pre-existing QS signals in the aquatic environment has been overlooked. QS signals cause detrimental effects on mammalian cells and induce cell death by interfering with multiple cellular pathways. Moreover, QS signals not only function as a messenger, but also annihilate the functions of the host immune system which implies that QS signals should be designated as a major virulence factor. Despite QS signals' role has been well documented in mammalian cells, their impact on aquatic organisms is still at the budding stage. However, many aquatic organisms produce enzymes that degrade and detoxify such QS signals. In addition, physical and chemical factors also determine the stability of the QS signals in the aqueous environment. The balance between QS signals and existing QS signals degrading factors essentially determines the disease progression in aquatic organisms. In this review, we highlight the impact of QS signals on aquatic organisms and further discussed potential alternative strategies to control disease progression. |
first_indexed | 2024-09-25T03:41:05Z |
format | Article |
id | upm.eprints-108865 |
institution | Universiti Putra Malaysia |
last_indexed | 2024-09-25T03:41:05Z |
publishDate | 2023 |
publisher | Wiley |
record_format | dspace |
spelling | upm.eprints-1088652024-08-12T07:17:13Z http://psasir.upm.edu.my/id/eprint/108865/ Quorum sensing signals: aquaculture risk factor Priya, P. Snega Boopathi, Seenivasan Murugan, Raghul Haridevamuthu, B. Arshad, Aziz Arockiaraj, Jesu Bacteria produce several virulence factors and cause massive mortality in fish and crustaceans. Abundant quorum sensing (QS) signals and high cell density are essentially required for the production of such virulence factors. Although several strategies have been developed to control aquatic pathogens through antibiotics and QS inhibition, the impact of pre-existing QS signals in the aquatic environment has been overlooked. QS signals cause detrimental effects on mammalian cells and induce cell death by interfering with multiple cellular pathways. Moreover, QS signals not only function as a messenger, but also annihilate the functions of the host immune system which implies that QS signals should be designated as a major virulence factor. Despite QS signals' role has been well documented in mammalian cells, their impact on aquatic organisms is still at the budding stage. However, many aquatic organisms produce enzymes that degrade and detoxify such QS signals. In addition, physical and chemical factors also determine the stability of the QS signals in the aqueous environment. The balance between QS signals and existing QS signals degrading factors essentially determines the disease progression in aquatic organisms. In this review, we highlight the impact of QS signals on aquatic organisms and further discussed potential alternative strategies to control disease progression. Wiley 2023 Article PeerReviewed Priya, P. Snega and Boopathi, Seenivasan and Murugan, Raghul and Haridevamuthu, B. and Arshad, Aziz and Arockiaraj, Jesu (2023) Quorum sensing signals: aquaculture risk factor. Reviews in Aquaculture, 15 (4). 1294 - 1310. ISSN 1753-5123; ESSN: 1753-5131 https://onlinelibrary.wiley.com/doi/10.1111/raq.12774 10.1111/raq.12774 |
spellingShingle | Priya, P. Snega Boopathi, Seenivasan Murugan, Raghul Haridevamuthu, B. Arshad, Aziz Arockiaraj, Jesu Quorum sensing signals: aquaculture risk factor |
title | Quorum sensing signals: aquaculture risk factor |
title_full | Quorum sensing signals: aquaculture risk factor |
title_fullStr | Quorum sensing signals: aquaculture risk factor |
title_full_unstemmed | Quorum sensing signals: aquaculture risk factor |
title_short | Quorum sensing signals: aquaculture risk factor |
title_sort | quorum sensing signals aquaculture risk factor |
work_keys_str_mv | AT priyapsnega quorumsensingsignalsaquacultureriskfactor AT boopathiseenivasan quorumsensingsignalsaquacultureriskfactor AT muruganraghul quorumsensingsignalsaquacultureriskfactor AT haridevamuthub quorumsensingsignalsaquacultureriskfactor AT arshadaziz quorumsensingsignalsaquacultureriskfactor AT arockiarajjesu quorumsensingsignalsaquacultureriskfactor |