Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa)
Blood cockle shells are a type of shellfish with distinctive bright red color that is commonly found in coastal areas of Asia, a rich source of protein, vitamins, and minerals, including calcium carbonate. Calcium carbonate (CaCO3) is a common mineral supplement that slowly paved its way into nano r...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Published: |
Universiti Putra Malaysia Press
2023
|
| _version_ | 1811137961126789120 |
|---|---|
| author | Mohd Thani, Suryati Sa’at, Azmah Abas, Razif Mohamad Zainal, Nurul Hayati Mohd Moklas, Mohamad Aris Mohamad Yusof, Loqman Mohd Thani, Nurfatimah Abu Bakar @ Zakaria, Md Zuki |
| author_facet | Mohd Thani, Suryati Sa’at, Azmah Abas, Razif Mohamad Zainal, Nurul Hayati Mohd Moklas, Mohamad Aris Mohamad Yusof, Loqman Mohd Thani, Nurfatimah Abu Bakar @ Zakaria, Md Zuki |
| author_sort | Mohd Thani, Suryati |
| collection | UPM |
| description | Blood cockle shells are a type of shellfish with distinctive bright red color that is commonly found in coastal areas of Asia, a rich source of protein, vitamins, and minerals, including calcium carbonate. Calcium carbonate (CaCO3) is a common mineral supplement that slowly paved its way into nano research to support bone health that also used in the treatment of bone infections due to its inherent properties; reduces inflammation, promotes bone healing, crucial role in the immune system, and slow degradability. The latest invention on CaCO3 from cockle shells, is an alternative mode of drug delivery to circumvent existing antibiotic resistance mechanisms and allow direct drug delivery to the target site, using locally sourced ingredients to reduce long-term high production costs. A top-down approach CaCO3 nanoparticles from blood cockle (Anadara granosa) shells were developed, known as calcium carbonate nanoparticles (CNPs). This research aims to characterize the morphology of CNPs from blood cockle shells via Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and Atomic Force Microscopy (AFM). Results:A homogeneously spherical CNPs. with a mean diameter of 36.5 ± 2.3 nm was observed on TEM, so as FESEM. From AFM, the mean diameter for CNPs was 38.6 ± 3.6 nm The CNPs were spherical in shape, homogenously scattered, less agglomerate, porous with rough surfaces. The size and morphology of the CNPs from blood cockle shells were suitable for transport carrier in situ bone infection, according to the results. |
| first_indexed | 2024-09-25T03:42:36Z |
| format | Article |
| id | upm.eprints-110152 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-09-25T03:42:36Z |
| publishDate | 2023 |
| publisher | Universiti Putra Malaysia Press |
| record_format | dspace |
| spelling | upm.eprints-1101522024-09-05T06:45:33Z http://psasir.upm.edu.my/id/eprint/110152/ Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) Mohd Thani, Suryati Sa’at, Azmah Abas, Razif Mohamad Zainal, Nurul Hayati Mohd Moklas, Mohamad Aris Mohamad Yusof, Loqman Mohd Thani, Nurfatimah Abu Bakar @ Zakaria, Md Zuki Blood cockle shells are a type of shellfish with distinctive bright red color that is commonly found in coastal areas of Asia, a rich source of protein, vitamins, and minerals, including calcium carbonate. Calcium carbonate (CaCO3) is a common mineral supplement that slowly paved its way into nano research to support bone health that also used in the treatment of bone infections due to its inherent properties; reduces inflammation, promotes bone healing, crucial role in the immune system, and slow degradability. The latest invention on CaCO3 from cockle shells, is an alternative mode of drug delivery to circumvent existing antibiotic resistance mechanisms and allow direct drug delivery to the target site, using locally sourced ingredients to reduce long-term high production costs. A top-down approach CaCO3 nanoparticles from blood cockle (Anadara granosa) shells were developed, known as calcium carbonate nanoparticles (CNPs). This research aims to characterize the morphology of CNPs from blood cockle shells via Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and Atomic Force Microscopy (AFM). Results:A homogeneously spherical CNPs. with a mean diameter of 36.5 ± 2.3 nm was observed on TEM, so as FESEM. From AFM, the mean diameter for CNPs was 38.6 ± 3.6 nm The CNPs were spherical in shape, homogenously scattered, less agglomerate, porous with rough surfaces. The size and morphology of the CNPs from blood cockle shells were suitable for transport carrier in situ bone infection, according to the results. Universiti Putra Malaysia Press 2023 Article PeerReviewed Mohd Thani, Suryati and Sa’at, Azmah and Abas, Razif and Mohamad Zainal, Nurul Hayati and Mohd Moklas, Mohamad Aris and Mohamad Yusof, Loqman and Mohd Thani, Nurfatimah and Abu Bakar @ Zakaria, Md Zuki (2023) Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa). Malaysian Journal of Medicine and Health Sciences, 19 (suppl.12). pp. 1-6. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/jurnal_kami/volume_19_2023/mjmhs_vol19_supp_12_november_2023-76567 |
| spellingShingle | Mohd Thani, Suryati Sa’at, Azmah Abas, Razif Mohamad Zainal, Nurul Hayati Mohd Moklas, Mohamad Aris Mohamad Yusof, Loqman Mohd Thani, Nurfatimah Abu Bakar @ Zakaria, Md Zuki Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title | Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title_full | Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title_fullStr | Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title_full_unstemmed | Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title_short | Morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells (Anadara granosa) |
| title_sort | morphological characteristic of calcium carbonate nanoparticles derived from blood cockle shells anadara granosa |
| work_keys_str_mv | AT mohdthanisuryati morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT saatazmah morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT abasrazif morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT mohamadzainalnurulhayati morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT mohdmoklasmohamadaris morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT mohamadyusofloqman morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT mohdthaninurfatimah morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa AT abubakarzakariamdzuki morphologicalcharacteristicofcalciumcarbonatenanoparticlesderivedfrombloodcockleshellsanadaragranosa |