Revealing metabolic and biochemical variations via 1H NMR metabolomics in streptozotocin-nicotinamide-induced diabetic rats treated with metformin

Revealing metabolic and biochemical variations via 1H NMR metabolomics in streptozotocin-nicotinamide-induced diabetic rats treated with metformin

The increasing prevalence of lean diabetes has prompted the generation of animal models that mimic metabolic disease in humans. This study aimed to determine the optimum streptozotocin-nicotinamide (STZ-NA) dosage ratio to elicit lean diabetic features in a rat model. It also used a proton nuclear m...

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Bibliographic Details
Main Authors:	Zolkeflee, Nur Khaleeda Zulaikha, Wong, Pei Lou, Maulidiani, M., Ramli, Nurul Shazini, Azlan, Azrina, Mediani, Ahmed, Tham, Chau Ling, Abas, Faridah
Format:	Article
Published:	Elsevier 2024

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