Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the j...
Main Author: | |
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Format: | Thesis |
Language: | English English |
Published: |
2000
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Online Access: | http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf |
_version_ | 1825944880479731712 |
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author | Mohd Taib, Nor Azizah |
author_facet | Mohd Taib, Nor Azizah |
author_sort | Mohd Taib, Nor Azizah |
collection | UPM |
description | The aim of the research is to develop an effective vaccine against vibriosis.
Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive
production activity of brackishwater ponds and cage-cultured fish. The
pathogenicity study of V alginolyticus was performed by challenging the juvenile
seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell
concentrations. All the isolates caused mortality to fish at a concentration as low
as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by
scanning and transmission electron microscopy, revealed the presence of
V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In
addition, the V .alginolyticus cells were observed in the spleen. These
pathological changes showed that V alginolyticus was responsible for the death of
the infected seabass. |
first_indexed | 2024-03-06T07:22:50Z |
format | Thesis |
id | upm.eprints-11211 |
institution | Universiti Putra Malaysia |
language | English English |
last_indexed | 2024-09-25T03:31:57Z |
publishDate | 2000 |
record_format | dspace |
spelling | upm.eprints-112112024-06-12T04:48:11Z http://psasir.upm.edu.my/id/eprint/11211/ Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus Mohd Taib, Nor Azizah The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the juvenile seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell concentrations. All the isolates caused mortality to fish at a concentration as low as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by scanning and transmission electron microscopy, revealed the presence of V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In addition, the V .alginolyticus cells were observed in the spleen. These pathological changes showed that V alginolyticus was responsible for the death of the infected seabass. 2000-08 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf Mohd Taib, Nor Azizah (2000) Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus. Masters thesis, Universiti Putra Malaysia. English |
spellingShingle | Mohd Taib, Nor Azizah Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title | Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_full | Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_fullStr | Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_full_unstemmed | Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_short | Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_sort | vibriosis vaccine development pathogenesis immunological and molecular characterization of vibrio alginolyticus |
url | http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf |
work_keys_str_mv | AT mohdtaibnorazizah vibriosisvaccinedevelopmentpathogenesisimmunologicalandmolecularcharacterizationofvibrioalginolyticus |