Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus

The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the j...

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Main Author: Mohd Taib, Nor Azizah
Format: Thesis
Language:English
English
Published: 2000
Online Access:http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf
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author Mohd Taib, Nor Azizah
author_facet Mohd Taib, Nor Azizah
author_sort Mohd Taib, Nor Azizah
collection UPM
description The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the juvenile seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell concentrations. All the isolates caused mortality to fish at a concentration as low as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by scanning and transmission electron microscopy, revealed the presence of V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In addition, the V .alginolyticus cells were observed in the spleen. These pathological changes showed that V alginolyticus was responsible for the death of the infected seabass.
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spelling upm.eprints-112112024-06-12T04:48:11Z http://psasir.upm.edu.my/id/eprint/11211/ Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus Mohd Taib, Nor Azizah The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the juvenile seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell concentrations. All the isolates caused mortality to fish at a concentration as low as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by scanning and transmission electron microscopy, revealed the presence of V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In addition, the V .alginolyticus cells were observed in the spleen. These pathological changes showed that V alginolyticus was responsible for the death of the infected seabass. 2000-08 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf Mohd Taib, Nor Azizah (2000) Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus. Masters thesis, Universiti Putra Malaysia. English
spellingShingle Mohd Taib, Nor Azizah
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title_full Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title_fullStr Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title_full_unstemmed Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title_short Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
title_sort vibriosis vaccine development pathogenesis immunological and molecular characterization of vibrio alginolyticus
url http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf
work_keys_str_mv AT mohdtaibnorazizah vibriosisvaccinedevelopmentpathogenesisimmunologicalandmolecularcharacterizationofvibrioalginolyticus