Optimization of osmotic shock process variables for enhancement of the release of periplasmic interferon-α2b from Escherichia coli using response surface method

The osmotic shock process for the release of periplasmic recombinant human interferon-α2b from Escherichia coli was optimized using response surface method (RSM). The process parameters such as pH, buffer concentration and sucrose concentration in hypertonic solution, cell concentration to hypertoni...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Ramanana, Ramakrishnan Nagasundara, Tana, Joo Shun, Mohamed, Mohd Shamzi, Tau, Chuan Ling, Tey, Beng Ti, Ariff, Arbakariya
פורמט: Article
שפה:English
English
יצא לאור: Elsevier 2010
גישה מקוונת:http://psasir.upm.edu.my/id/eprint/11265/1/Optimization%20of%20osmotic%20shock%20process%20variables%20for%20enhancement%20of%20the%20release%20of%20periplasmic%20interferon.pdf