Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathw...
| Main Author: | |
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| Format: | Thesis |
| Language: | English English |
| Published: |
2002
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| Online Access: | http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf |
| _version_ | 1811137297921343488 |
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| author | Ban, Kechen |
| author_facet | Ban, Kechen |
| author_sort | Ban, Kechen |
| collection | UPM |
| description | Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of
the ten most common cancers in Malaysia. However, the molecular mechanisms that
contribute to tumour progression in hepatocarcinogenesis remain unknown.
In recent years, the evidence that the Wnt signaling pathway may play a crucial role in
the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this
area of research, the relationship between the related genes of Wnt signaling pathway is
still far from comprehensive.
By employing immunohistochemistry and DNA sequencing, some related proteins and
genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent
liver specimens from a tertiary referral centre in Malaysia. |
| first_indexed | 2024-03-06T07:23:00Z |
| format | Thesis |
| id | upm.eprints-11271 |
| institution | Universiti Putra Malaysia |
| language | English English |
| last_indexed | 2024-09-25T03:32:04Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | upm.eprints-112712024-06-13T07:11:31Z http://psasir.upm.edu.my/id/eprint/11271/ Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma Ban, Kechen Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia. 2002-10 Thesis NonPeerReviewed text en http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf Ban, Kechen (2002) Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma. Doctoral thesis, Universiti Putra Malaysia. English |
| spellingShingle | Ban, Kechen Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title | Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title_full | Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title_fullStr | Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title_full_unstemmed | Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title_short | Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma |
| title_sort | wnt signaling pathway related genes in hepatocellular carcinoma |
| url | http://psasir.upm.edu.my/id/eprint/11271/1/FPSK_P_2002_1.pdf |
| work_keys_str_mv | AT bankechen wntsignalingpathwayrelatedgenesinhepatocellularcarcinoma |