Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital
The acceptability of latent tuberculosis infection (LTBI) therapy remains low among healthcare workers (HCWs). Up to 10% of LTBI cases can reactivate into active tuberculosis, posing risks to HCWs and patients. Understanding HCWs’ intention to undergo LTBI treatment is crucial for designing effectiv...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2024
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/113601/1/113601.pdf |
| _version_ | 1825940349992828928 |
|---|---|
| author | El Seifi, Omnia Samir Zakaria, Wan Muhammad Zainol Mansor, Zawiah |
| author_facet | El Seifi, Omnia Samir Zakaria, Wan Muhammad Zainol Mansor, Zawiah |
| author_sort | El Seifi, Omnia Samir |
| collection | UPM |
| description | The acceptability of latent tuberculosis infection (LTBI) therapy remains low among healthcare workers (HCWs). Up to 10% of LTBI cases can reactivate into active tuberculosis, posing risks to HCWs and patients. Understanding HCWs’ intention to undergo LTBI treatment is crucial for designing effective management policies, especially where no LTBI policy exists. This cross-sectional study investigated the intention to receive LTBI therapy and its associated factors among HCWs in a Malaysian teaching hospital. The study was conducted from 5th to 30th May 2023, in a hospital without an LTBI screening program. Stratified random sampling was used to select HCWs, excluding those undergoing TB or LTBI therapy. Respondents completed a questionnaire measuring intention to receive LTBI treatment, LTBI knowledge, attitude, perceived norm, and perceived behavioral control. Of the 256 respondents, the majority were female (63.7%), under 35 years old (64.45%), had no comorbidities (82.0%), and worked in clinical settings (70.3%). However, 60.5% of respondents had low LTBI knowledge and 60.5% held unfavorable attitudes toward LTBI treatment. Despite this, 53.5% of respondents intended to undergo LTBI therapy if diagnosed. Factors positively associated with this intention included being female [aOR: 2.033, 95% CI: 1.080–3.823], having high LTBI knowledge [aOR 1.926, 95% CI: 1.093–3.397], had favorable attitude [aOR 3.771, 95% CI: 1.759–8.084], and strongly perceiving social norms supportive of LTBI treatment [aOR 4.593, 95% CI: 2.104–10.023]. These findings emphasize the need for an LTBI management policy in the teaching hospital. To boost HCWs’ intention and acceptance of LTBI treatment, a focused program improving knowledge, attitude, and perception of social norms could be introduced. |
| first_indexed | 2024-12-09T02:26:45Z |
| format | Article |
| id | upm.eprints-113601 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-12-09T02:26:45Z |
| publishDate | 2024 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | upm.eprints-1136012024-11-14T03:47:52Z http://psasir.upm.edu.my/id/eprint/113601/ Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital El Seifi, Omnia Samir Zakaria, Wan Muhammad Zainol Mansor, Zawiah The acceptability of latent tuberculosis infection (LTBI) therapy remains low among healthcare workers (HCWs). Up to 10% of LTBI cases can reactivate into active tuberculosis, posing risks to HCWs and patients. Understanding HCWs’ intention to undergo LTBI treatment is crucial for designing effective management policies, especially where no LTBI policy exists. This cross-sectional study investigated the intention to receive LTBI therapy and its associated factors among HCWs in a Malaysian teaching hospital. The study was conducted from 5th to 30th May 2023, in a hospital without an LTBI screening program. Stratified random sampling was used to select HCWs, excluding those undergoing TB or LTBI therapy. Respondents completed a questionnaire measuring intention to receive LTBI treatment, LTBI knowledge, attitude, perceived norm, and perceived behavioral control. Of the 256 respondents, the majority were female (63.7%), under 35 years old (64.45%), had no comorbidities (82.0%), and worked in clinical settings (70.3%). However, 60.5% of respondents had low LTBI knowledge and 60.5% held unfavorable attitudes toward LTBI treatment. Despite this, 53.5% of respondents intended to undergo LTBI therapy if diagnosed. Factors positively associated with this intention included being female [aOR: 2.033, 95% CI: 1.080–3.823], having high LTBI knowledge [aOR 1.926, 95% CI: 1.093–3.397], had favorable attitude [aOR 3.771, 95% CI: 1.759–8.084], and strongly perceiving social norms supportive of LTBI treatment [aOR 4.593, 95% CI: 2.104–10.023]. These findings emphasize the need for an LTBI management policy in the teaching hospital. To boost HCWs’ intention and acceptance of LTBI treatment, a focused program improving knowledge, attitude, and perception of social norms could be introduced. Public Library of Science 2024 Article PeerReviewed text en cc_by_nc_4 http://psasir.upm.edu.my/id/eprint/113601/1/113601.pdf El Seifi, Omnia Samir and Zakaria, Wan Muhammad Zainol and Mansor, Zawiah (2024) Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital. Plos One, 19 (7). art. no. e0307199. pp. 1-19. ISSN 1932-6203 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0307199 10.1371/journal.pone.0307199 |
| spellingShingle | El Seifi, Omnia Samir Zakaria, Wan Muhammad Zainol Mansor, Zawiah Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title | Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title_full | Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title_fullStr | Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title_full_unstemmed | Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title_short | Intention to receive Latent Tuberculosis Infection (LTBI) treatment and its associated factors among healthcare workers in a Malaysian teaching university hospital |
| title_sort | intention to receive latent tuberculosis infection ltbi treatment and its associated factors among healthcare workers in a malaysian teaching university hospital |
| url | http://psasir.upm.edu.my/id/eprint/113601/1/113601.pdf |
| work_keys_str_mv | AT elseifiomniasamir intentiontoreceivelatenttuberculosisinfectionltbitreatmentanditsassociatedfactorsamonghealthcareworkersinamalaysianteachinguniversityhospital AT zakariawanmuhammadzainol intentiontoreceivelatenttuberculosisinfectionltbitreatmentanditsassociatedfactorsamonghealthcareworkersinamalaysianteachinguniversityhospital AT mansorzawiah intentiontoreceivelatenttuberculosisinfectionltbitreatmentanditsassociatedfactorsamonghealthcareworkersinamalaysianteachinguniversityhospital |